ID A0A0V1HG46_9BILA Unreviewed; 1205 AA.
AC A0A0V1HG46;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=Anion exchange protein {ECO:0000256|RuleBase:RU362035};
GN Name=SLC4A10 {ECO:0000313|EMBL:KRZ09562.1};
GN ORFNames=T11_14518 {ECO:0000313|EMBL:KRZ09562.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ09562.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ09562.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ09562.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004554}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362035}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362035}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993, ECO:0000256|RuleBase:RU362035}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ09562.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDP01000071; KRZ09562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1HG46; -.
DR STRING; 268475.A0A0V1HG46; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR013769; Band3_cytoplasmic_dom.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR003024; Na/HCO3_transpt.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR NCBIfam; TIGR00834; ae; 1.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF36; ANION EXCHANGE PROTEIN; 1.
DR Pfam; PF07565; Band_3_cyto; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR PRINTS; PR01232; NAHCO3TRSPRT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU362035};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362035};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362035};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362035};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362035}.
FT TRANSMEM 517..536
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 605..626
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 633..653
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 737..760
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 781..802
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 834..853
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 874..891
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 935..954
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 966..987
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT DOMAIN 146..433
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 486..1012
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1160..1205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1205 AA; 135770 MW; 0F5FEAA1DE919122 CRC64;
MDDKKGAAVN ETDDVVRDTK ADEQNISDKD QMESRRSDIV WFGTGIHLPY DNDKAKEHIP
LERRQRRRRP TLLVSKDSDR MTPVEEDRIA MAPSARVQQL LNQQKNGENL EWQPSHSLFT
EMEFLYGTGP NQEWRETARW VKYEEDVEEG GNRWSKPHVA TLSLHSLFEL RSCLMNGVVI
LDVDATELET VIEHTISTLL SEGLLKQSAV NTVREALLSK HKHQYEQNKV HKEGMSSGQS
FLQTVRSIAD IGRSLSHAKN MAPSVVESSA VSQIPAPVSP TALNVPDIGL NKLSGTALSA
KQGSRVMDGS DITAKGNYHL YKKLPRGAEA SNVLVGQLSS LDNYISAFIR LNKACHFNNL
TEVPVPTRFM FILLGPEGHK LKYREIGRAI STLMSDEVFC DVAYQARNRE DLLDGIDEFL
EQVIVLPPGE WDPKIRIEPP TSVPSQEGRK KLVPKKEDAQ GSQNNNFDDD ISGGHGKDIA
LKRTHKLFGG LMADVKRKIP WYVSDFKDAF NLQCVAAFLY MYFAMLAPIV TFGGLLEEAT
DRNLAAIENL FSGAICGTLY SLFAGQPLTM IGSTGPVLIF ERVVFELCKK ASLDFLSVRF
WINTWSGVIL VIIVAFDASA MVSYITRFTE ESFSALISFI FIYESIAKLI KILQNARIIE
WNPHSATGGG GNCSCSGKPL ESEFMDNVKS MVSRRRMNAS SWLFHQPDEN ISYIDWDNVP
LEHCEYLNGQ LNGDSCYYML DVFLMSLVLL AGTFAIATVL KHGRNSSYFP TSVSTIETVR
TILSDFAVFI AISLMILLDY FVGLQTPKLY VPENFSPTLE SRGWIVHPLP DPSTWWIIPL
GIAPAVLLCI LLFMDHQITV VIVNRKENKL KKGCGYHLDL LLIAIVCFIT AFMGLPIFVA
ATVMSVSHVN ALRVESECRA PGEKPKFIGV REQRVTGTLV FLFIGFSTLM TSVLKHIPMP
VLYGVFLYMG VSSLSGVQMV DRLLLLFMPM KYQPDYIYLR HVPIRRVHLF TFFQITCFVI
MCVVKEVEVT SVAFPLMLVV LVAIRKLLEY VFTEKELKLL DDQMPEITLR KREDAKKKRQ
KEQQEEANKL VPVQTTSNLH IPLASGHVMS IPLESLNAEE KVNLSEEVNR SGLWKHIASY
SDMTKNMKKM KANDQKELKT FEEEEDDGEA ITISFDRAEE TPSTEKKPLL NDTEPLNEND
EMSRM
//
