ID A0A0V1I8H7_9BILA Unreviewed; 1750 AA.
AC A0A0V1I8H7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE SubName: Full=GTPase-activating protein pac-1 {ECO:0000313|EMBL:KRZ18848.1};
DE Flags: Fragment;
GN Name=pac-1 {ECO:0000313|EMBL:KRZ18848.1};
GN ORFNames=T11_9579 {ECO:0000313|EMBL:KRZ18848.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ18848.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ18848.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ18848.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ18848.1}.
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DR EMBL; JYDP01000002; KRZ18848.1; -; Genomic_DNA.
DR STRING; 268475.A0A0V1I8H7; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01253; PH_ARHGAP21-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041681; PH_9.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23175; PDZ DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23175:SF23; PDZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF15410; PH_9; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000055024}.
FT DOMAIN 694..816
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 959..1151
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 96..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1468..1493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1530..1608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1635..1660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1719..1750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..115
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1530..1555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1566..1608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1729..1743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ18848.1"
SQ SEQUENCE 1750 AA; 193351 MW; 9D1A056C78645E57 CRC64;
LNICITSTDE HFSKNPPCQC CYYFESKTSG SNSESVCMMT ENLNSCSLNN EEEQLLNVEQ
KEKWENSSTG YCEEEHNNKA VGRLDLACWK RTNDDSVGDA GKQQEEEEEE DAAVDATKDD
ASLNDSLKLA TWKRDLASRS NGLVSSRTVP WCLRRGSVKT GVVSQIVEAL RENRKLDENC
CCSSSSSSSA QLGCCYATTS AKDNKYYYYA NRRFNNSTTT TTAAAAATVA ASDSCLVRTL
ISLYETGTVD RVGPLKLYHA QMYKRELNRI TSHNLGQVLR KAKRFDQLLS GPRRHSLDSN
QIFDSFVDNY HNSTTTTTTT NVNGLTDNQG QIRCRAMSTF LDESFPTNRP DVLTCRLRRQ
QSFIRAVTGN KLLTSATTTT TTPPLAGRQA ALCFTAFALL HHVYLTSYMH IYINNAAQIG
ELTKILMLLT KAGTGDLASN LSSRVDALYA TVASMARKLT SVIVPIASIQ LTCLLALPAC
IGPDDRWLDN YRLLNMSIHK LLYCCYCLRF ANVYAPQLYI DTINEYTDQS SSSVNRAYPA
DGRSKKQSTN RSMPNGNILS SQAAIQNGRR HSTLKLMDAL GKVEVMEKSC LANGNAAIPC
SSQTTVPCSA RIPVPPGKDQ ILSPPFVRYR QQGSREKRIT RFINFYNSCQ DQVDNFTSET
CSPSPSCSSS FSDSSCAKPT TLSPCSDSTS RSDTVYREGI LYHKQVAVEN GRRAHDRSWQ
LYWAFLIDHR LYLCPEKPML AVPPTALSFD KVANFVREKA ALLIDVRSCI ADIAYSHLKR
KNVFRCITVN QSEHLFQAMD EKDMIGWIAT LQSCAVMEET ETVSPSSLAL IIKHYERQSH
SLSPSVKLKK PTTLHRVVTA AKERNTAAAA TTTNASLMDD ASHDQQTATD LNRDEASAVV
ASSSSSSSFG QLAHSKLEKG EATLKKVKKW CKTRKAAAGP ATVVSSQVNN PKVNAVFGIN
LEDCVTTGET DFVPLIVQLC VKVVEAYGLD TVGVYRIPGN TAAVNTLSAN LDQGFEFVEF
DDIRWRDVNV VSSLLKAFFR KLPDPLLTSA LYRDFIEANR IESLESRLKA FRELIFKLPK
HNFETLKFLL QHLKRVVAHS SVNKMEVKNL ALMFGPSLVR PSGENMVTMV THMSDQCKIV
ELLLSHSDWI FGSDWSASLD NQSEQTKSLD HSSSNVGELL NLIHHSEKEF LYIAVFCYEL
ILSNILINEF ITKRKCFIMD FSNLDKVKEN LARNLQNVKM VKSGYLAPSS TAQAIQQQQQ
CFNTADYDER NIDEEVARAE RLHSLSVECC TPSLLNSRRL SAGVGDPLTI SARSSTTNEL
IQAAEDYRKS REEQIYTARR IFIAGTSAVD SVHNSPPVDS VAKIDGLARH CRHLNVNPNS
LDVLSPETRE KIKQFQRGHP LWSSSSARSS NNVLATTGPQ FSSNNDNKND VNLRQHNDEL
IAYSESDVRK KNIDDMLMNR SCQARLGYSA NSSKSNTPGA TVTDRAFNNS NSNGTTYQHG
ASILAKESYP ATSFICGSSI SSSGMHDQSR LVESNLSKPI SSPATDSSSS SSAFLRRHVI
MRRPAQLESV STNREQNKNV KNLPTSPPST AIINTTTTTP SSSSSCSSRS TILRNYGQSS
FDSAMPAKFS HLLKLNNRKS SSPQAGGGNK RRDARRHTLG NVDCGGIVGV KLSSSSIPST
VTAPTRWSIE AVTGMHGGVG ASTASVECKA RQEDDHALKQ RCLKRRSVRR SNPNLSSPPL
NFDPALQVHS
//
