ID A0A0V1KX35_9BILA Unreviewed; 845 AA.
AC A0A0V1KX35;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Protein Skeletor, isoforms D/E {ECO:0000313|EMBL:KRZ51888.1};
GN Name=Skeletor {ECO:0000313|EMBL:KRZ51888.1};
GN ORFNames=T02_11933 {ECO:0000313|EMBL:KRZ51888.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ51888.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ51888.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ51888.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ51888.1}.
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DR EMBL; JYDW01000210; KRZ51888.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1KX35; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR019545; DM13_domain.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24036; SKELETOR-RELATED; 1.
DR PANTHER; PTHR24036:SF5; THROMBOMODULIN; 1.
DR Pfam; PF10517; DM13; 2.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00686; DM13; 2.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51549; DM13; 2.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..845
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006881320"
FT TRANSMEM 44..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 208..316
FT /note="DM13"
FT /evidence="ECO:0000259|PROSITE:PS51549"
FT DOMAIN 333..445
FT /note="DM13"
FT /evidence="ECO:0000259|PROSITE:PS51549"
FT DOMAIN 716..776
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 718..777
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ51888.1"
SQ SEQUENCE 845 AA; 96692 MW; 2C8942CE6D8B3BE8 CRC64;
MAMHCNLISC FILATLTVHA TPFFDRAFRQ AKRCFEKSVY PIGTLFYADY VYAASLVPNW
WKLAEPRLNT SIAVLGIAPL RFTTTSTIIS AVTLIPAESV DPASPFHCNN SSFIKPSYLL
PASSLILQLT FACLLLDKRK TRPGRHYIHL PIQPICCSTD FPFTPLGIFL VIIHLRMLLH
PLLAQLLIIL ASFCNVLTAL PEPEPWFGDF LGTLPDPQKI GIFGKVYAVN STCVQILNFT
YNGQAPDLFF WMDTETIPSA RGVKLSTFES GDSMLTPYYN KHVVLILPPN VALSDYKTFG
LWCQSCTQDF GHIRIPDGFT PPNPQFLTHG LKATTKGVRY NVGSGPILIL DRRTVKIYGL
TFQGNRAPDS FFFVGKGSEP RRNDGIKVPI RGKDSPTDIS NLKELYNGEK DIILELPEDH
DIYNIDWISI YCLRFAVNFA FVKIQAISDR IPPYVPVPVQ RSKIPEFKRE PWTTVTLLGK
PPRNNFTFQL GPPGGLRAYE SWAKAKPGEF VWYVNGYMAP ELWVQRGVTY KIRVEGGDDS
VLERFFNPLY ISDDPYGGYS KLTDDDRQQI TVYAGLNKQN LPLDGNGRLC RFINRHPEII
PDRLDSFLEY RKNLVLRCLK NSPGIFYWTP DDRTPDVVYY QSYTNFNMGW KIIVTDEIPS
DVPFTEQESY SYELLDSEDE QLYSQHRDPL LQGNAGIRPK RQCNGRSNEI SMLSHQAKRR
PRVLFTQRQV QQLESRFKQQ HYLTAFERDE MAKKLKLTSH QVKIWFQNRR YKFKRVRQDK
TLELTVNFPK LHHSSLPLLL QPGEAYQTSK NPFDCRFLTS QTVSSHFLIS SALPHSCTTQ
CMPIQ
//
