ID A0A0V1MCX1_9BILA Unreviewed; 1586 AA.
AC A0A0V1MCX1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE SubName: Full=Rho GTPase-activating protein 39 {ECO:0000313|EMBL:KRZ69376.1};
DE Flags: Fragment;
GN Name=nft-1 {ECO:0000313|EMBL:KRZ69376.1};
GN ORFNames=T10_4188 {ECO:0000313|EMBL:KRZ69376.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ69376.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ69376.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ69376.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ69376.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDO01000138; KRZ69376.1; -; Genomic_DNA.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR009688; FAM210A/B-like_dom.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR45876; FI04035P; 1.
DR PANTHER; PTHR45876:SF8; FI04035P; 1.
DR Pfam; PF06916; FAM210A-B_dom; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054843}.
FT DOMAIN 52..79
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 1010..1170
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1181..1369
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 139..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 941..973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..215
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..748
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ69376.1"
SQ SEQUENCE 1586 AA; 178195 MW; 34AA269D87895BEE CRC64;
LWYMMADSQI EWVEIVEPQT REHMYANLIT GECAWDPPPG ARIKKTHENQ WWELYDQNTG
RFYYYNASTQ KTVWQRPYNC DIIPLAKLQT LKQNTEARHR TSAARQHVSP PVQMELHGNA
VLYDEPLFSV PNESINSPCT TASSLSPHSS RSSTQTSTTT RKPETKTVSC QTQTSPLASP
KARKRVNKTK GCQTALSASH LVKKHNHRTG GGGGRSRSRS RRNVANSTEP EDSIQEALIV
SLNKDKRNAD FRNTKETINE RPVENGIEND RPSAGSSLDR CSSSSCTDAA TNSRRFDPMI
GSMSSYSLQM NSCCADSHRI NVEVGKFLRR HDSKLSSSHR VDELPNQQFF KGSSSTPPRR
RQLDQKQCKA STSCLDSSSS FVRSFLAPNN SSTTSTNTTK NAAVPVPAVR QSLKLHSEQS
QLPNLGNLSR QRSFDFACNF NQLRLYGGKD GKKFESGSED EEEEDADSTA TTTAATTSTA
NNNDEDGNEV NKEEEEKKLT VDDGEAEIQL RKEVSEEKNS MVMKTHGASN NTTNAAAACG
GGGGSGKSAK KVLLKTANVC HSKARVVPAT ASMSGSPQLW KAIDNSTCTA GTAAVWKSHD
SGIKSGDSGA RGDDSSSAAS VESPRFGHLD SAGNVFKSSG TACKLAKFPV SLNRPVSPNV
NKISQQQQQQ QQQQRQTTPR MGIAFVNSIA PAYEHVTKHL TYSQLHQQFI VGDSIDQFSE
REVEESSSSS NDDSAPDDDD DEGLFADDEE GGPPSPVSLS SQDDDDDDID DNNEVLVSKS
CLSSKKYLLP TMGVSQRFLD PDDTRLRVIY DTPDTLSKES KSTTPHDCGA EPPLLDSVLY
RRRSSDAGNF NVPKLNTVVS CSNNSMADDE NGSTKRLKNV VEKPARSSMN GFLSTADLSP
NQYRPQSVLM PVHQEHYLAP TNVIVNHSST LNRLNKAECT RTTTSGPMHH HHQQQQQHQQ
HQQQQQHQQQ QQQLLRLRES DVELYPHEYL NRHKKGLFGK RQSVQSMLSW TRAELKKPLI
MTVDKAVKKE AREIFKRIQA YMGDRKVKKS TITVDMLALD VCVRGWAKPA LRDEIFIQLC
KQTTENPRPE SVRRGWELMS ICLKFFPPSS QFTSYLDTYI SRYADPVLDL PEVSVSHYAQ
HCCKRLERIL RHGARRGLRK PTIEEVEQAR LQIFHPSMFG NTLDEVMVIQ RERFTGRKLP
WIQTTLSELV LQLNGARTEG IFRVPGDIDE VNALKMRIDR WLLPPVADPH IPASLLKLWY
RELADPLVPD CLYQECIQTV DEPLKSCEIA DRLPSINRLV LAYLIRFLQI FIRPENVVHT
KMDSSNLAMV MAPNCLRCQS DDPTVIFDNT LTCCSRSWRG LKLNFMRNYA FNRNPLLKFE
KSVPWKYGSL SHNSRCTFSV SCIQYHRSLA SLESSKSNGL QPDKKADVDE SKLTTYQKFK
LTFKRYWYVL VPVHLITSSV WLGSFYYLAE SGVDLVGILE SMGFSEQILN RLKQAPRAGN
IALAYAMFKI VTPLRYTATI GVTAVSVKYL VRMGLIKPAP SKEQVKRFVE QKRFQLRERY
KIESNKLKGK WKNISKISSK RNRLDD
//
