ID A0A0V1MV34_9BILA Unreviewed; 897 AA.
AC A0A0V1MV34;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Bifunctional coenzyme A synthase {ECO:0000313|EMBL:KRZ75627.1};
DE Flags: Fragment;
GN Name=COASY {ECO:0000313|EMBL:KRZ75627.1};
GN ORFNames=T10_3162 {ECO:0000313|EMBL:KRZ75627.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ75627.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ75627.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ75627.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ75627.1}.
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DR EMBL; JYDO01000036; KRZ75627.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1MV34; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.
DR CDD; cd02022; DPCK; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00376; Dephospho_CoA_kinase; 1.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR001977; Depp_CoAkinase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR002347; SDR_fam.
DR NCBIfam; TIGR00152; dephospho-CoA kinase; 1.
DR PANTHER; PTHR43157:SF69; DEHYDROGENASES, SHORT CHAIN; 1.
DR PANTHER; PTHR43157; PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF01121; CoaE; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51219; DPCK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 507..643
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ75627.1"
SQ SEQUENCE 897 AA; 101088 MW; 53057BEEBD1318A2 CRC64;
LLFDKIEMVG FHEFDSSLIL VVIAILCVIL GRFYFKGSQF YGKEKCKGRI YVVTGANSGI
GKEIVRELNY RGAVVYMACR SKERGYSAID DLVKLGCSAD RLHILELDQS SFASVTAFVD
KLQALTDKLD GIVLNAGVMY VPRYQLTNDG HEYIWQVNYL STVLLCESLL PLLEKCRDEG
RVVIVSSNAH IWINDLNIQS IDRRNYWNSV KAYGRSKLAQ VMYTVARSAM LRREGYLVTI
NACHPGIINT PLFRQLPILG NSVFQSVLAP FLWYFLKNAK DGAQTPLYCL LSKELGGVSG
KYFCELKQAE VNPLVDNSEA RQALFDCTLE ACNLVKDDKA VLRFQMNSTG LLLLTQRSST
LKIGIEFLLL KACQHVKGTL FISVHENLVR QLTTENIFNF VQHTYNASCS LDKSLDVRLM
VDSFKRVGDC KRKLNPETCL LLDCDLSQLG DFFTSKERMH LPMQMVMLHF DKQLVDMSCL
PTQMNTFCSM EKFSKAPQTL PMYKHIVLGG TFDRMHDGHK FLLTIALLLT KRRLTCGITC
GSMLTKLIQP VKERCKIVEQ FLADVDPSVR LDIVPIEDSF GPSIDDASMD CIVGSEETAS
GILRVNEKRK NKNLPELAAY AVSLLQVTQK NNVGKLSSSE ARKQLLGSTL RPFKKLTLKS
KSKPYIIGLT GGIASGKSKI AEYLNHWGAC VIDCDKIGHQ SYSPNTVVYE KLVNAFGKRI
INRCTGEIDR GCLGKIVFSN PAALKELNEI VWPEILSLVK LQVDSVKERR KIVVIEAAVL
IQAGWQNFVD EVWASFIPAD EAVKRLVERN KLTEEDARRR LNAQLSNDEI IKNAHIVFCS
LWHYDCTRMQ ALRICISILL RKHGVICGNA LICDHSAQQF KILDLFKLIN KSWDIII
//
