ID A0A0V1P1D1_9BILA Unreviewed; 524 AA.
AC A0A0V1P1D1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE SubName: Full=Regulator of G-protein signaling 7 {ECO:0000313|EMBL:KRZ90009.1};
GN Name=RGS7 {ECO:0000313|EMBL:KRZ90009.1};
GN ORFNames=T08_11598 {ECO:0000313|EMBL:KRZ90009.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ90009.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ90009.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ90009.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ90009.1}.
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DR EMBL; JYDM01000061; KRZ90009.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1P1D1; -.
DR STRING; 92180.A0A0V1P1D1; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF5; REGULATOR OF G-PROTEIN SIGNALING 7-LIKE PROTEIN; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 20..95
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 312..430
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 454..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 60456 MW; 09B47B8B10C38EE7 CRC64;
MSSFPMFRKM DELCIQMMKP DSGLPIKGQK YFRTSVPSSF TGSELIEWLM TNLEEVDQAE
ALHLANQLSA FGYLFSVFDA SAPVKEDNCL YRLQIPYFWP SSNMQPDSIE YAIFLSKRLL
RNEEKHGLVE YEAESYQKLR ELLGHMWDFV QSQAEMQLKL FKEKKKSEKV VFDSQEKAYW
RIHRPPVEPG TVCCIEESYG KLEKRIKKKC IKDYQRDVRN YSVDCFQFLK TVQCVQIERL
KQILKTKPWL KSPKSLETLV SWCDQFSNYD PMLTPPRDPG NPWIVDDPTL WQLNANNVEV
PTERRVRRWG FSIHELIKDP IGRQVLETFL ESEFSQENIR FWLAVQDLKY SPSSEVNAKV
AAIYNEFLVA GAPCQVNVDS QTLETVTKAL KDQTVPLRYC FSQAEEHIFI LMSKDSYPRF
ARSEIYRSML AAAQQQGSKK LGWRSFLFGG NHGPLKKSQT SRTSPQGFYK NRDEGSTARL
QNVVDMTKKS TLEPGDAISG TQPKNSPTFT CDGADSLDVE VPLK
//
