ID A0A0V1PAD4_9BILA Unreviewed; 1814 AA.
AC A0A0V1PAD4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Protein polybromo-1 {ECO:0000313|EMBL:KRZ93042.1};
GN Name=PBRM1 {ECO:0000313|EMBL:KRZ93042.1};
GN ORFNames=T08_7422 {ECO:0000313|EMBL:KRZ93042.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ93042.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ93042.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ93042.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ93042.1}.
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DR EMBL; JYDM01000029; KRZ93042.1; -; Genomic_DNA.
DR STRING; 92180.A0A0V1PAD4; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0016586; C:RSC-type complex; IEA:InterPro.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR CDD; cd21984; HMG-box_PB1; 1.
DR Gene3D; 2.30.30.490; -; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 6.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR037382; Rsc/polybromo.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16062:SF19; PROTEIN POLYBROMO-1; 1.
DR PANTHER; PTHR16062; SWI/SNF-RELATED; 1.
DR Pfam; PF01426; BAH; 2.
DR Pfam; PF00439; Bromodomain; 6.
DR Pfam; PF00505; HMG_box; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00439; BAH; 2.
DR SMART; SM00297; BROMO; 6.
DR SMART; SM00398; HMG; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF47370; Bromodomain; 6.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS51038; BAH; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 5.
DR PROSITE; PS50118; HMG_BOX_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 51..121
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 208..278
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 360..430
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 523..593
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 713..783
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 980..1100
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 1187..1303
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 1380..1448
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 1461..1491
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DNA_BIND 1380..1448
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 139..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1419..1446
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 145..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1814 AA; 208250 MW; EF01BCF210AD8E17 CRC64;
MKRDHSVDES TMADVPMAKR LRRSALSSAA EEQARLCREL FTSLREFTNS EGAYISRPFL
RLPSKKSLPE YYSVIENPID LTQIHEKVKT DEYSHVDRFM EDINLLVENA KRFYGEGSSE
YADASELWNQ IVELRSKQEY NSDSHSEIST RSPESSPSRS SRSYRSFSPH RLHRTKENPS
PMSGCEPVSA HVFEHLLASV LRERSEGGGR LLCDAFRLLP SKELWPDYYE TIRDPIDLQL
IAKRVRSGRY RNLNDIERDF NLLCRNARLF NEPGSQVYRD AKTIRKFILK KKAELLDVGC
KSIDRNLMSN DSAVVDRLLN LTEKDLAMEE DSDDEQLPLE TERQVKYLYS FLRNWRENGA
DQSIVEPFLR LPDKRTNAEY YNNVESPVSF FVINKRLKNG CYENVNALLE DIVQLCSNAK
ATNLQNSFLY NVSELRAVKL EELACRKVRE MNNMPGTSEP CTSTSTGRAD YLEVDDSESG
FSSVNSPAVQ MDTTSTELDE SQAVFKEKLL TVFNAVVNYR DETGRFVASA FMEKPSKKLY
PDYYKVIPEP IDLNTIRNAI EADKYSSSQA LAADFELLFE NARHYNEDYS VIYTDANTLN
RIFLATMSRV CPTPIYSTKA NHFINRGRKS FSRESTLGSC LRLRSGSDAA NTITTTAITA
PSVATNIAAA TASPVQQRFQ RAAAARGVGM CNNNLEVKLQ TLFRRVRDYA DCRGRVLSTM
FQKLPPKSDY PDYYEVIKKP IDLQKIQSRI MLGQYERLDA LVADLALVFD NACKYNDPES
QIYKDALMLQ RVMLLKQAEL QSDEKTRGSV NVQVAVQELL MNLFLGMQTY IGSQGRCVFD
SFYRMQEIFD VDKESLTFER IKRNLEKKRY RRMDRFQQDI FHLFSEIRRY KGPGDQMWND
AIELQTFFIR TRDQLAKRGE WFYSPAMAFS EKDLHREVEE DCKAFKLRSE IEEKRDHLKT
LLSKHKLGDI DMTKHEWNGV CYCIGDFAYV KPIDSNSTRM HIMQIHRLWK DSGTNEMMVF
GRWLYQPWET YHLLSRTFLQ NEVFLSEKFD HIDAKRLSGK CCVLFIKKYL QYRVLNFDEK
DVYVCESLYI KRGKQFRKLL TWDTDLPGAE WLQLEERSEP LVPVRVPSIF AQTNEQQQSS
AGNVSFEDFD HDCSVLQMER VEVVAPNDNS NQTGEVDFEQ LYAQEGIWLK LGDSVYVRNS
DGDSKIVFVE RLWKAGNNQA FLSGVTFVDP SRVEHEPTRL FYRNELFALD NSQSFPVSSV
YGLCAVLSYK DYCAFRPTEL TEEQIYLCDL RVVLGQQSKL IIPESHEKKF RFKAFRLSAD
VLEDEILFFK KTVLPEKVAS PYLMKRELAM NMDDYVADSP DQDSSDQFMF HDIQSTPKLT
SRSKSGYILF SAVARKRIMA ENPDCSFGSI SKIVGAEWKK LSKSEKKRYE EEAQRIAEER
EKADADVGGR FHLLPGQIRV YCCRWKDCDY QFENAEQLNE HVTNVHTAQI GNNNSNNSWH
SYAFCRQKIY DNLFVRSVET GDNQYVCLWH TCTKYRKDGR PFPSMPRLHR HIREKHVPAS
AKCIYAQNRS RNYMPLAVVD SPRACDNFSP STQPTVVPQV AQSILAAQLL SQPVAQTTQG
GVYPYPTTPL QSVHYSHNVE ASTHAIHPEN SRLIYENQNM PLYAALPQNS AARIPAEVAN
LHSNIEANVV AETNQPLYGI QEGSVVVQPG QQQMMDRFGA PVQQAPSSSA AAEESLLPVF
VAIPKKPNPI SSDAAVYLSA IEGILSGASS RSGNVVHVGK YFSKIPQTDE ELIQGYLRMQ
RRLFLEGQET RGMQ
//
