ID A0A0V1PKC4_9BILA Unreviewed; 423 AA.
AC A0A0V1PKC4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Inhibin beta chain {ECO:0000313|EMBL:KRZ96620.1};
GN Name=Actbeta {ECO:0000313|EMBL:KRZ96620.1};
GN ORFNames=T08_12009 {ECO:0000313|EMBL:KRZ96620.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ96620.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ96620.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ96620.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ96620.1}.
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DR EMBL; JYDM01000007; KRZ96620.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1PKC4; -.
DR STRING; 92180.A0A0V1PKC4; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF263; PROTEIN DECAPENTAPLEGIC; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..423
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006884276"
FT DOMAIN 295..423
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 423 AA; 47955 MW; 5241677A76B241E9 CRC64;
MNMLLRNWIF IAFHLCVKFQ IDAIGCCGSL TNDSSISQSE KQKPFKEILA SMDRLHQLLT
VKRIVEELNI PLPLPNHTSP KYTSLAQIAF HETVEIGQSS LNGQSSVSVI TFEIAGIPTD
GNDKWVGSND DHHNHHHHDE LLHHKITMNM SSSYTSNGRL VAAELVVPLL QGQQPCRALF
ERISWSGSNG TDRTWTNRID RSACEPFNVT LPLVELWTNW PVGMTTVFDV AIRILGHKLH
ARNYKHLTPV LRVRIHQNHQ QVDFGSSRPK RSKQMIKWNA KKKPTANRFD VVDCEKQWDA
AFLSSTSPAV YDDLMPCCRR RFRISFDELG WGDWVLAPKQ FHSYYCIGRC TGFGGEFPTD
GGADGFAFYS ELMNLYRSTE KNYMKPCCSP IQFAPLTIAI WQGPNEQATQ TLDNVVVTKC
GCI
//
