ID A0A0W0GHR6_9CHLR Unreviewed; 472 AA.
AC A0A0W0GHR6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:KTB48082.1};
GN ORFNames=DEALK_09270 {ECO:0000313|EMBL:KTB48082.1};
OS Dehalogenimonas alkenigignens.
OC Bacteria; Chloroflexota; Dehalococcoidia; Dehalogenimonas.
OX NCBI_TaxID=1217799 {ECO:0000313|EMBL:KTB48082.1, ECO:0000313|Proteomes:UP000053947};
RN [1] {ECO:0000313|EMBL:KTB48082.1, ECO:0000313|Proteomes:UP000053947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP3-3 {ECO:0000313|EMBL:KTB48082.1,
RC ECO:0000313|Proteomes:UP000053947};
RA Key T.A., Richmond D.P., Bowman K.S., Cho Y.-J., Chun J., da Costa M.S.,
RA Rainey F.A., Moe W.M.;
RT "Genome sequence of the organohalide-respiring Dehalogenimonas
RT alkenigignens type strain (IP3-3T).";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTB48082.1}.
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DR EMBL; LFDV01000002; KTB48082.1; -; Genomic_DNA.
DR RefSeq; WP_058439118.1; NZ_QEFQ01000002.1.
DR AlphaFoldDB; A0A0W0GHR6; -.
DR STRING; 1217799.DEALK_09270; -.
DR PATRIC; fig|1217799.6.peg.953; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000053947; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000053947}.
FT DOMAIN 11..144
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 185..417
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 472 AA; 54434 MW; 1F90DAB5B406B4A5 CRC64;
MRVLLVNPAK RFKGFLGKTR SLQPTVLPNS LLYIGAVLER GGHQVMIWDQ QVDDRKSTDF
FAAFNPQIVG FSVSVGGIIY EAIEQSKEFK SLDPSIKIVW GNVHPSMLPE QTLAEDYVDF
VVIGPGEYTL LELTDHLGKK GTPATLAEIN GLAFRDNGKI IVNPDRPFIQ NLDELPDPAW
HLVPMEDYWE KSLNTSRGCP SKCIFCYNPP FHKGQLGEFS AERIVSQMET LKNRYGVTLF
RFFEDDFCHN RPRLHTFCKL VIEKKMKIRW DCDARAGLTE EDVSLMKRSG CASVGFGVES
GSPRLLKFIR KTAKLEDIKQ TFKLLVKHKI LPKLYLISEL PTETVADFEA TKTLIKELGN
PPYQYVSFLP YPGTELYNYC VARGLEPPKT TEEWAAFISQ PDCGIRWSEV PKEMTAEFKQ
KLVKYYFWRR TFFALRHGMF SFYIPVNPSP KEFFRVIRFW WRYYVTRPIT GH
//
