ID A0A0W0R2J1_9GAMM Unreviewed; 430 AA.
AC A0A0W0R2J1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=3-oxoacyl-ACP synthase {ECO:0000313|EMBL:KTC65242.1};
GN Name=fabFc {ECO:0000313|EMBL:KTC65242.1};
GN ORFNames=Lade_1425 {ECO:0000313|EMBL:KTC65242.1};
OS Legionella adelaidensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=45056 {ECO:0000313|EMBL:KTC65242.1, ECO:0000313|Proteomes:UP000054859};
RN [1] {ECO:0000313|EMBL:KTC65242.1, ECO:0000313|Proteomes:UP000054859}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1762-AUS-E {ECO:0000313|EMBL:KTC65242.1,
RC ECO:0000313|Proteomes:UP000054859};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Identification of large and diverse effector repertoires of 38 Legionella
RT species.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTC65242.1}.
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DR EMBL; LNKA01000005; KTC65242.1; -; Genomic_DNA.
DR RefSeq; WP_058462507.1; NZ_LNKA01000005.1.
DR AlphaFoldDB; A0A0W0R2J1; -.
DR STRING; 45056.Lade_1425; -.
DR PATRIC; fig|45056.6.peg.1471; -.
DR OrthoDB; 9808669at2; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000054859; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Reference proteome {ECO:0000313|Proteomes:UP000054859};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 3..424
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 430 AA; 45783 MW; DEB6E9D56B44BD23 CRC64;
MNQRRVAITG LGVVSPIGNN VGATWENLMA KKSGIANISH FDASGFPTHI AAEVKNFKPT
YPQQGKHHRY SMDFTRFALE AATEAFNDAG VFPTKENASR WGIVTGSGMM TAEFEYINRF
QEFCAPQGEV EWPLLEENGS SFFNLVDFGK TTSNSGLSLL IQQFGIAGYA NSVHTACASG
GQALGLAMQV IRRGDADFML AGGFDSMINP IGVSSFCLLG ALSTYNDIPE AASRPFDGTR
NGFVLGEGAA FLILEEWNKA KARGAKIYAE LAGEGNSLSS YRITDSHPNG DGAVQAIEQA
LKDAGVSPSM VDYINAHGTS TKMNDLSETN AIKAVFGEQA YKMPVSSTKS QTGHLIAAAG
ALEAVISVLA INKGHVPMTA NLCSPDPECN LDYVVEGPRE KSLGVVLSNS FGFGGSNSCL
LFKHPQFEGK
//
