ID A0A0W0XQF7_9GAMM Unreviewed; 509 AA.
AC A0A0W0XQF7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Alpha,alpha-trehalase {ECO:0000313|EMBL:KTD46941.1};
DE EC=3.2.1.28 {ECO:0000313|EMBL:KTD46941.1};
GN Name=treF {ECO:0000313|EMBL:KTD46941.1};
GN ORFNames=Lrub_1863 {ECO:0000313|EMBL:KTD46941.1};
OS Legionella rubrilucens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=458 {ECO:0000313|EMBL:KTD46941.1, ECO:0000313|Proteomes:UP000054608};
RN [1] {ECO:0000313|EMBL:KTD46941.1, ECO:0000313|Proteomes:UP000054608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WA-270A-C2 {ECO:0000313|EMBL:KTD46941.1,
RC ECO:0000313|Proteomes:UP000054608};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-
CC glucose; Xref=Rhea:RHEA:32675, ChEBI:CHEBI:15377, ChEBI:CHEBI:15903,
CC ChEBI:CHEBI:16551, ChEBI:CHEBI:17925; EC=3.2.1.28;
CC Evidence={ECO:0000256|ARBA:ARBA00001576};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD46941.1}.
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DR EMBL; LNYT01000020; KTD46941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W0XQF7; -.
DR STRING; 458.Lrub_1863; -.
DR PATRIC; fig|458.5.peg.1943; -.
DR Proteomes; UP000054608; Unassembled WGS sequence.
DR GO; GO:0004555; F:alpha,alpha-trehalase activity; IEA:UniProtKB-EC.
DR GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR001661; Glyco_hydro_37.
DR InterPro; IPR018232; Glyco_hydro_37_CS.
DR PANTHER; PTHR23403:SF6; CYTOSOLIC NEUTRAL TREHALASE-RELATED; 1.
DR PANTHER; PTHR23403; TREHALASE; 1.
DR Pfam; PF01204; Trehalase; 1.
DR PRINTS; PR00744; GLHYDRLASE37.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00927; TREHALASE_1; 1.
DR PROSITE; PS00928; TREHALASE_2; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:KTD46941.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KTD46941.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054608};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..509
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006916746"
SQ SEQUENCE 509 AA; 58922 MW; 2480087D3D587F6A CRC64;
MQKWMSYWII LLLISGFSSR AAAVKDRMTE QVKAYVESTW DVLVRDTNQL DWSHADDKLN
STQTILYISR RENLQHIKNR VAGTSKSAKK PVIIRTLPED VSHIQEHGLL YLPHPYVVPG
GRFNEMYGWD SYFIQLGLLE SGRLQLARCM VDNLIYEINH YGTILNANRT YYLQRSQPPL
LTGMILAYYR RTHDKQWLET TLPAINTFYQ FWVSPPHLNA ETGLSRYYAQ GEGPAPEESE
TYYQNVLRYF KTHNIRDYDK SLYYDANRGT LTPAFYLADR TVRESGLDIS NKYGPFGAAI
VDYIPVDLNV FLYQMEKETG EIYTLLNRSK SASVWQKRAS QRAARINQYL WDNQRGFYFD
YNHKTKQLRP YLFATTLYPL WAGLATKEQA KAVVRNLPLL MGKGGLLASP YKQGVQWDAP
FGWAPMHYFA VEGLKRYGYR SEALDLAQRF VNTVNKGFAK TQAVFEKYDV LDESIHTSGK
IHYSYTSNEV GFGWTNGVYL LFLNELDAA
//
