ID A0A0W0ZZ15_9GAMM Unreviewed; 422 AA.
AC A0A0W0ZZ15;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=GTP cyclohydrolase II {ECO:0000313|EMBL:KTD74330.1};
GN ORFNames=Ltuc_2177 {ECO:0000313|EMBL:KTD74330.1};
OS Legionella tucsonensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=40335 {ECO:0000313|EMBL:KTD74330.1, ECO:0000313|Proteomes:UP000054693};
RN [1] {ECO:0000313|EMBL:KTD74330.1, ECO:0000313|Proteomes:UP000054693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49180 {ECO:0000313|EMBL:KTD74330.1,
RC ECO:0000313|Proteomes:UP000054693};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD74330.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LNZA01000001; KTD74330.1; -; Genomic_DNA.
DR RefSeq; WP_058521295.1; NZ_LNZA01000001.1.
DR AlphaFoldDB; A0A0W0ZZ15; -.
DR STRING; 40335.Ltuc_2177; -.
DR PATRIC; fig|40335.7.peg.2318; -.
DR OrthoDB; 5482269at2; -.
DR UniPathway; UPA00275; -.
DR Proteomes; UP000054693; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003935; F:GTP cyclohydrolase II activity; IEA:InterPro.
DR GO; GO:0009231; P:riboflavin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00641; GTP_cyclohydro2; 1.
DR Gene3D; 3.40.50.10990; GTP cyclohydrolase II; 1.
DR InterPro; IPR022163; GTP_CH_N.
DR InterPro; IPR032677; GTP_cyclohydro_II.
DR InterPro; IPR000926; RibA.
DR InterPro; IPR036144; RibA-like_sf.
DR PANTHER; PTHR47259; -; 1.
DR PANTHER; PTHR47259:SF2; URACIL-REGULATED PROTEIN 1; 1.
DR Pfam; PF12471; GTP_CH_N; 1.
DR Pfam; PF00925; GTP_cyclohydro2; 1.
DR SUPFAM; SSF142695; RibA-like; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KTD74330.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054693}.
FT DOMAIN 13..201
FT /note="GTP cyclohydrolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12471"
FT DOMAIN 227..377
FT /note="GTP cyclohydrolase II"
FT /evidence="ECO:0000259|Pfam:PF00925"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 46451 MW; 4B789C2BE316E071 CRC64;
MVQDGSKKKS KGHIVLSSHP SGHTAAPLKI KWGAENPKER GPVIASLTNI KNRNAVGTHS
GSYSVYRALA VAAGVLDPEH VPDLTDTTPP VAIGPHPQWN DTQKIVSMDP WGHLVASVFS
EEIQAGYDIR PTIAVTKAHI NIPELHTAIQ KGRLKPDGKI LKESGDVAVT KVAVEPVWYL
PGIAARFEVS ESLLRRTLFE QTAGMFPELV TRSDLDVFLP PIGGLTAYFF GDVTTIHNPQ
IELTCRIHDE CNGSDVFGSD ICTCRPYLVH GIELSIESAQ KGGAGLIVYN RKEGRALGEV
TKFLVYNARK RQKGGDTAAK YFERTECVAG VQDMRFQELM SDILHWLGIT KIHRFVSMSN
MKYDALLKSG IHVIERVTIP DELIPLDAQV EMNAKRAAGY YSPDRIVDIN ELAKTKGRDL
NE
//
