ID A0A0W4ZX07_PNEMU Unreviewed; 790 AA.
AC A0A0W4ZX07;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KTW32903.1};
GN ORFNames=PNEG_04290 {ECO:0000313|EMBL:KTW32903.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:KTW32903.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTW32903.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFWA02000007; KTW32903.1; -; Genomic_DNA.
DR RefSeq; XP_019613375.1; XM_019757809.1.
DR AlphaFoldDB; A0A0W4ZX07; -.
DR STRING; 1069680.A0A0W4ZX07; -.
DR GeneID; 19896412; -.
DR VEuPathDB; FungiDB:PNEG_04290; -.
DR eggNOG; KOG0955; Eukaryota.
DR OMA; LANHAYA; -.
DR OrthoDB; 163389at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006338; P:chromatin remodeling; IEA:UniProt.
DR CDD; cd04369; Bromodomain; 1.
DR CDD; cd15670; ePHD_BRPF; 1.
DR CDD; cd15492; PHD_BRPF_JADE_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF164; BROMODOMAIN-CONTAINING PROTEIN, 140KD, ISOFORM A; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 261..311
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 315..425
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 627..678
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 767..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..790
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 790 AA; 93164 MW; A80626EE6E85C875 CRC64;
MVPRIDYKGE SSCFSNSAHA SRLAVINENN YEQITEKPRE ERSYLEFYTN FNINEPLRII
YSKDDHNSTV PLLSDDLNSS EIRKSYGELN QENDFDRNYD KCLGSKITKK EKHIFDSDMS
CDISKQDKKS ESKDEQLKNI ENPYIQKSSK FSFRNIQPFE KEARYTGRSI MEYGYQEADI
WNRPSDTYIR FVEESKETLA NRVEYDMDEQ EQYNSKRLKS EGDTISHELF EIVLTKIEKE
WIELDKRMPK DQSKENLSPD DSKCSICDDG ECENVNAIVF CDGCNLAVHQ DCYGIPYIPE
GQWLCRKCLI SPQNTLNCIF CPNTSGAFKQ TSDNRWAHLL CAIWIPEVTV MNTVYQEPID
NIHKIPASRW KLICYICQQR MGASIQCVNK SCYRAFHVTC ARRAKLYMPM KKNNTELKAY
CDKHVPSFWR NEHDIAKFLY DTRKQFLSYT PSTSEFVENN HNSNYIHGAS SKIYINLKKA
KTYPLIPVYI QNRILDYIHK FPIRKKSIFI TDICKYWSLK KESRKNASLI KRLQLKTENE
IRNLSTDQLS ERIEFAKILK HDLEKLLELT DSVKKREEEK KKISCYLETM ADGLYFPITH
IIRYILNCIE GWDKNKLFSN IPIDTFNYNS INGMPTSLSM ISKKIEDREY ANLLQFKTDL
MHVFDNAIKY NDHNTIYYKT AVKFKRQCEK LFLDAENSIS FLKMENERMV SDWSIFEPKG
LSIKEYVQIW PGDDIRTMSP LSEIADEEFN LLERHVNLIQ KKDNLNKQNM KNDIKKKSKH
NLRSRPQKFK
//
