ID A0A0W7WT10_9ACTN Unreviewed; 507 AA.
AC A0A0W7WT10;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Peptidase C69 {ECO:0000313|EMBL:KUF13738.1};
GN ORFNames=AT728_00130 {ECO:0000313|EMBL:KUF13738.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF13738.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF13738.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF13738.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF13738.1}.
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DR EMBL; LOCL01000062; KUF13738.1; -; Genomic_DNA.
DR RefSeq; WP_058851499.1; NZ_LOCL01000062.1.
DR AlphaFoldDB; A0A0W7WT10; -.
DR STRING; 1765722.AT728_00130; -.
DR OrthoDB; 9803213at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF10; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 33..97
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 253..498
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 507 AA; 54582 MW; 701EAFED0ABFE454 CRC64;
MPHSIDSAFT ALPLRALADA ALARARALGA EHADFRLERV RSASWRLRDA RPAASSDSTD
LGYAVRVVHG GAWGFASGVD LTMDAAARVA SQAVAMAKLS AKVIEAAGSD ERIELAAEPV
HADRSWVSSY EIDPFSVPDE EKTGLLAEWS GRLLAAEGVA HVDATLLTVH ENKFYADTAG
TVTTQQRVRL HPQLTAVAVD ESSGEFDSMR TLAPPVGRGW EYLTGSTWDW QGELERIPEQ
LAEKMRAPSV EAGRYDLVVD PSNLWLTIHE SIGHATELDR ALGYEAAYAG TSFATFDQLG
KLAYGSSLMN VTGDRTAEHG LATIGYDDEG VAAQSWDLVK DGTLVGYQLD RRIAKLTGFE
RSNGCAYADS PGHVPVQRMA NVSLRPDPAG LSTEDLISGV DRGIYVVGDR SWSIDMQRYN
FQFTGQRFYK IENGRLAGQL RDVAYQATTT DFWGSMTAVG GPDTYVLGGA FNCGKAQPGQ
VAAVSHGCPS ALFTSVNILN TTQEAGR
//
