ID A0A0W7X3S9_9ACTN Unreviewed; 490 AA.
AC A0A0W7X3S9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:KUF17508.1};
GN ORFNames=AT728_08720 {ECO:0000313|EMBL:KUF17508.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF17508.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF17508.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF17508.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF17508.1}.
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DR EMBL; LOCL01000033; KUF17508.1; -; Genomic_DNA.
DR RefSeq; WP_058847974.1; NZ_LOCL01000033.1.
DR AlphaFoldDB; A0A0W7X3S9; -.
DR STRING; 1765722.AT728_08720; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 157..485
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 490 AA; 52766 MW; 7C142DE30CC115CA CRC64;
MNTTVRRTAV FCGVLVLALL IRATWVQFVR GDALAEHDMN RRVKIDTFAQ PRGDIIVGGR
SITGSVPTPG SDFKYKRVYK DGPMYAPVTG YFSQSQGKTF LEGVHDDLLS GKDRRLLGSP
LDTLTGERPA GGDVITTIDP KAQRAAYKGL TDLNAKGAVV ALDPRSGRIL AMASTPSYDP
SVFAGIFNKD GKAFKKLDED KRKPLNSRAF RETYPPGSTF KILTAAAALE HGAVTDIDTR
SKARAPYRLP LSSTTIGNVV PDSMCDKVSL KTAMQWSCNN VFLDAALRTG KDGMRETAEK
FGFNEEQFMP VRTAASVYPE KLDKPQTALT GMGQGSVTTT PFQMAMVTAG LANDGKVMQP
YLVKELRGSD LSTVAKTEPK ELSRAVSEST ARKVQEMMEH TVTDGTGDKV AIEGVTVGGK
PGTAQHGANV RDERPYAWFV SYAKKSDGTS PVAVAVLVDP QDMDISRSEI AGGKLGAPIA
KAVMEAVLKR
//
