ID A0A0W7X652_9ACTN Unreviewed; 968 AA.
AC A0A0W7X652;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Regulator {ECO:0000313|EMBL:KUF18312.1};
GN ORFNames=AT728_24845 {ECO:0000313|EMBL:KUF18312.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF18312.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF18312.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF18312.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF18312.1}.
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DR EMBL; LOCL01000031; KUF18312.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W7X652; -.
DR STRING; 1765722.AT728_24845; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..92
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 835..868
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..92
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 243..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 968 AA; 103551 MW; D9D35B514BF8701E CRC64;
MPPLRFQVLG PVRVWCGDEA LPEGRPQERA LLTALLLRAG RTATASELID AIWGQAPPAQ
ALPALRTYAS RLRKALGRRT LVSEAGGYAI DLPDGSLDLA ECERHEAQAA EARAAHDPHR
ARQALRAALA LWNGEPLGGV PGPFADAQRS RLTEWRLALL EHRLALDLEL GGHLDAVSEL
TSLTAEHPLR EGLRALLMLA LYRGGRQSEA LGVYADTRRM LDEELGVGPG PELTALHQRV
LHADPGLAPP PGSRGEDDQP VQPTHLAQLP ADLADFTGRT AAAAQLRREL LRDPGRVMAI
ASVRGLGGVG KTTLAVRVAH AVRGHFPGGQ LYADLLGQSA RPARPHDVLG AFLRALGVPD
SALPDDHGER AALYRSTLAG RRVLVLLDNA HGEAQVRTLL PGAPGCAVLI TSRARLVAVP
GAQVLDLDVM TEREALALFA RIVGAPRAEA EPAACRETVA ACGYLPLAIR IAAARLVARP
AWAVSTLAGR LADERRRLDQ LRLGDLAVDA TFELGHGQLE PAQARAFRRL ALPDGLDISL
AAAAAVLDET EDTSERLLES LVDTGLLESA APGRYHYHDL LRLFARDRAL RADPAGDRGA
ALSRLLGFYL ATACHAYALE NPGDRLVAHL APTARRALPF TGRQQALDWL FSEGPALLAA
VRQCAAEAEL APMAADVLLV AQDLMESGAH RQTYASAASA VAEEARRGGD ARTEGRARVV
LGQVHHLAGR VERAREEAER AHALGAAADD ALTLGYAQNL LGLLAIFHGR HQAAAACFTR
ALSAFRADGN RYGETAMLMN LGRAQLGLGQ IEAAIAASEQ SVELWRGLGA TLRLANGYYA
LGLALHEAGR YDEALKRFRQ GLVIFQESRQ PYWIGMTHFR MATAHLAASR AHVAAAHADR
ALVLLRDIGG DRRLAAVLSL LARTLLLLGQ QERAHTCWQE ALSLFERIGS PEAAHVRALL
APAGNPAR
//
