ID A0A0W7X7R9_9ACTN Unreviewed; 416 AA.
AC A0A0W7X7R9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Diaminopimelate decarboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AT728_06225 {ECO:0000313|EMBL:KUF18658.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF18658.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF18658.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF18658.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600183-50};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|RuleBase:RU003737}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF18658.1}.
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DR EMBL; LOCL01000029; KUF18658.1; -; Genomic_DNA.
DR RefSeq; WP_058846815.1; NZ_LOCL01000029.1.
DR AlphaFoldDB; A0A0W7X7R9; -.
DR STRING; 1765722.AT728_06225; -.
DR OrthoDB; 9802241at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:UniProt.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR002433; Orn_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR43727; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR PANTHER; PTHR43727:SF2; DIAMINOPIMELATE DECARBOXYLASE 1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR PRINTS; PR01182; ORNDCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 26..275
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 276..376
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
FT ACT_SITE 349
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT MOD_RES 48
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ SEQUENCE 416 AA; 43688 MW; 33B399E93FD7E0B6 CRC64;
MTENAFLLNL AARYGTPLYA YDLPAVRRAA AALRSDLPAG SRILYSVKAN PHPLLIETLR
TEGCEAEVSS VGELAVAIAA GHAPERVLYS GPGKSPSDLR TALASGVRTF SVESVTDRQR
LDALAQDADV RCDYLVRLNG PAGSVHGSLR MSGSASAFGA DVADMEALRA LLTVRSRTRP
IGLHTFFATN IGNEDSLIAE FQQAVRTVSE VCRETEFVPH MIDLGGGFPA PQAAPGGVTR
HPRLASAVEG ALDAHLVTRR TSGVEIAFES GRYLVGAAGT LITEVLDVKR SRGRTFAVLD
TGVNALGGMS GLGRLMAPQA RPYRLAPAPT RDVPSGDEPC PVTLVGPLCT PLDVLNRSVD
LGEVRVGDLL AVPNVGAYGL TASLVGFLSH PLPTEIVHDG GTVVAARRLA LAEVHL
//
