ID A0A0W7YX76_9BURK Unreviewed; 565 AA.
AC A0A0W7YX76; A0A1V3TNN7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Long-chain fatty acid--CoA ligase {ECO:0000313|EMBL:KUF39693.1};
GN ORFNames=AS359_06515 {ECO:0000313|EMBL:KUF39693.1};
OS Comamonas kerstersii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Comamonas.
OX NCBI_TaxID=225992 {ECO:0000313|EMBL:KUF39693.1, ECO:0000313|Proteomes:UP000053300};
RN [1] {ECO:0000313|EMBL:KUF39693.1, ECO:0000313|Proteomes:UP000053300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12322-1 {ECO:0000313|EMBL:KUF39693.1,
RC ECO:0000313|Proteomes:UP000053300};
RA Ming D., Wang M., Hu S., Zhou Y., Jiang T.;
RT "Complete genome sequence of a multi-drug resistant strain Acidovorax sp.
RT 12322-1.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF39693.1}.
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DR EMBL; LPXH01000035; KUF39693.1; -; Genomic_DNA.
DR RefSeq; WP_058880220.1; NZ_MPOF01000013.1.
DR AlphaFoldDB; A0A0W7YX76; -.
DR STRING; 225992.B5M06_16135; -.
DR Proteomes; UP000053300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KUF39693.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053300};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 259..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..418
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 472..549
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 565 AA; 62931 MW; DCFB349E8EE2D526 CRC64;
MRLHDQHWPR RVPRTLTAPA TSLWDNLETS ARRYPDKVAL QFFGRTISYR ELADGAQRLA
ACLHAAGVQR GDRVILFMQN LPQLVMAHFA ILRANAVVVP VNPMNRAQEL QHYITDAGVR
LAMTTADLAP ELAQASAALP HEHRLQHMVV SQVGEYLPPE AEREPVPEAW QAWLTTQHPL
PALECGEVLN WQQALACTQP VPSLEVGPQD LSVLPYTSGT TGLPKGCMHT HASIMCNAMA
SAVWGQATSE NVALAVIPMF HITGMVAMMH AMVYVGGTMV LMPRWDRELA GRWISKYRIT
NWTNIPTMVI DLFASPNFRQ FDLSSLTYIG GGGAAMPQAV AQRLYDEFRL RYQEGYGLTE
TAAPSHNNPP ENPKQQCLGI PFIGTDSRII DPDTLQEVPV GEQGEIVISG SQLFQGYWRN
EAATRAAFIE LDGKRFFRTG DLGRMDEDGY FFITDRLKRM INASGFKVWP AEVESMMFLH
PAIQEACVIA ARDAYRGETV KAVVVLRPQY RGQVTEDDIT SWCRGHMAAY KVPRMVSFVD
ALPKSGSGKV MWRVLQEAEQ SCPTA
//
