ID A0A0W8D7N3_PHYNI Unreviewed; 689 AA.
AC A0A0W8D7N3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Acetyl-coenzyme A synthetase 1 {ECO:0000313|EMBL:KUF91970.1};
GN ORFNames=AM587_10017596 {ECO:0000313|EMBL:KUF91970.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF91970.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|EMBL:KUF91970.1, ECO:0000313|Proteomes:UP000052943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF91970.1}.
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DR EMBL; LNFO01001386; KUF91970.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W8D7N3; -.
DR STRING; 4790.A0A0W8D7N3; -.
DR EnsemblProtists; KUF91970; KUF91970; AM587_10017596.
DR OMA; MPNTWQT; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943}.
FT DOMAIN 58..113
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 116..499
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 566..644
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 689 AA; 76391 MW; C3E95C8A199AD6AE CRC64;
MAVLGKRKGD EVPAHDAKRA KDEAPLWTPP SDLVASSNWT KFTELVNKRF KLSLKTPQEL
WEWSVDNLED FWGACWDFTG MAASQPYSNV IEDKEKMPGA KFFPGARLNF AENLLRFRDD
RPAIIFKAET SNQEDVISYK ELYDRVAALS ARLAEMGVVA GDRVAAFIPN IPEAIIAMLA
TTSLGAIWSS CSPDFGAQGV LDRFAQITPK VMFTTDGYFY KGNRIDIFPQ VKKIIDELPT
VEKVVVIRFT VSKAHDLDLS TIRNAIYYDR FIEEAVELVK DPIPFAQLPF DHPVYVMYSS
GTTGLPKCLV QGPGVVLNHL KELSIHLNIQ REDRVFYYTT TGWMMWTWLV STLGVGATIV
LFDGNPLYPS TDALWKYAQD VGMTVFGTSA RYLAAVMDSG CIPGKKFDLS KLKLITSTGS
PASTNIFKFV YEGIKSNVQF ASISGGTDLN GCFALGCTNL PVCDSELQTR GLGLDVRIFN
DDGQEIVLEQ GELVCKQPFP SMPLYFWNDE SGAKYHGAYF DTFPNIWKHG DFAEVTKSGG
VIIYGRSDAT LKPGGVRIGT ADIYKVLEKM AEVADSVVVG QSYTLNDGTP DVRILLFVVM
TEGYECTPAF QKKVRQRIRD QTSPRHMPGM VVACPAIPHT VSGKKVELTV KKIIDGHAVT
NKNALQNPES LAWFEEFATS LRENSANGA
//
