ID A0A0W8DW12_PHYNI Unreviewed; 984 AA.
AC A0A0W8DW12;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Polyamine oxidase 4 {ECO:0000313|EMBL:KUG00546.1};
GN ORFNames=AM587_10014757 {ECO:0000313|EMBL:KUG00546.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUG00546.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|EMBL:KUG00546.1, ECO:0000313|Proteomes:UP000052943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the flavin monoamine oxidase family.
CC {ECO:0000256|ARBA:ARBA00005995}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUG00546.1}.
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DR EMBL; LNFO01000633; KUG00546.1; -; Genomic_DNA.
DR STRING; 4790.A0A0W8DW12; -.
DR EnsemblProtists; KUG00546; KUG00546; AM587_10014757.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:InterPro.
DR Gene3D; 3.90.660.10; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR PANTHER; PTHR10742:SF405; PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE; 1.
DR Pfam; PF01593; Amino_oxidase; 2.
DR Pfam; PF00150; Cellulase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..465
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
FT DOMAIN 477..600
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
FT DOMAIN 689..957
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
SQ SEQUENCE 984 AA; 110773 MW; 6BA4DB6961BBF04C CRC64;
MAVKSTIDLK SSYRVVVVGA GMAGVSVANA LLVSNEFAAS DVCVLEAQSR IGGRIRTQPF
SDSLPVNVEV GAAWIHGTEG NPFTDMAKKF GIVFKEVAPR NPWLHPGACK NFLFFDGDKQ
LPQEQVDETW QWQDLLMHKL QALATSPNAA DHQEKALSAI VDHLVASDEE LGEAMKAPNA
RARLDMCLKL IEVWMGVNDD EVQLDDFTDI ELIGDDAGAH CIVPAGMEHF IDHLAEPVKE
SIHTNVVVTS INYEDKDGVV IECSDGRRVS ADHVVVTSSL GFLKSGKLHF QPELPAAKLG
AIERSKMGQY MKILVEFPEI FWPENSTFIA QIKNSSVSSD AMDRRIYFPV VFNYQFAKGV
PIIEGVLVGE NASKISATFT EEEIAHALFL QLQETFGPNI PRPVNHFITR WDXDPWSIGA
YSSLTVDSTD EDPAILRQTV ANRVLFAGEA TDYKYQGALQ AAYLSDSSDG RHIYFPLVFN
YHLAKGVPIL EGVLIGDNAS AISASFTDEE IAHALFLQMQ ETFGPAVPKP INHFITRWDQ
DQWSVGAYSC VTARNAHEDP DLLKQTVANR VLFAGEAVDP KYQGALQAAY FTGLEAAAEL
VTQNLRSRSY QMSCVASDSL QARLRRGEVP CRGVNLGGWL VAEHWMTWDS CLWHGVPDAI
KNQGEFATMK FLGHEEGDRR FDEHRRSWIT EYDIAEMKRF GLNTVRVPVG YWIMGFDPTD
FPNKQEWTVF APHSLRYLDE LVNHWCVKYD MAVIVDIHAA KGSQNGRDHS AAVDSGVKYW
GQYPENVDNT VYLAKFLASR YRFCPSFLGI GLLNEPEHPT EQHVLRAYYE RAYSEIRATG
NDCVLTVAPL LTEQSPPFME DFMRYPKYFN VWHEWHPYFI WGYEGQNREQ VLQAVRRYGD
QISSWSGNWL LIDEWSLGAQ GCAFPSEDRY GLQQFASAQL EAFSKAHSGW IFWSWRHSDD
GHNRPTGWSM RQLLRDGVMR LYDV
//
