ID A0A0W8DW20_PHYNI Unreviewed; 1335 AA.
AC A0A0W8DW20;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Phosphatidylinositol 4-kinase {ECO:0000313|EMBL:KUG00616.1};
GN ORFNames=AM587_10010326 {ECO:0000313|EMBL:KUG00616.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUG00616.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|EMBL:KUG00616.1, ECO:0000313|Proteomes:UP000052943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUG00616.1}.
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DR EMBL; LNFO01000614; KUG00616.1; -; Genomic_DNA.
DR STRING; 4790.A0A0W8DW20; -.
DR EnsemblProtists; KUG00616; KUG00616; AM587_10010326.
DR OMA; YIPQLCT; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05168; PI4Kc_III_beta; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR Gene3D; 1.25.40.70; Phosphatidylinositol 3-kinase, accessory domain (PIK); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR042236; PI3K_accessory_sf.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048:SF22; PHOSPHATIDYLINOSITOL 4-KINASE BETA; 1.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00915; PI3_4_KINASE_1; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KUG00616.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1039..1320
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 752..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 814..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..650
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..714
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..779
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..850
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..874
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..894
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 943..960
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..988
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 148443 MW; F9A7AAA86D4E1F6A CRC64;
MEVTTMPEGS TPVAAAALKR LQINEDSSDD NRSEDWGADE SDWRTSSSSE PAARFSLIAL
PSKVRDSVFR RDRKPQRKTK DRSSTADTTV TSSANSTPRD SELITKTQQE LENVEKFRIF
WDEKLRNTMD RLAGTKTKQX DVEDDVFHLL LKLYAHQDVV AQLYSSYEAN AAEFEFYIPQ
LCTFLIHGNY AKQHQLECFL MSRSGDSLPF AHRLTWFLRS FCDDAKEYQS EYLSVTASQD
QENSDLLTAI GMRAGVPALL MNRGLCVEEV SAAKPHNLEK RRSIIFPTDN DLDSSTLETD
ETFAGHLLSK RNSIQDEARA EEGNSQQILL FKQTPKFVEA LTDLADQLIP TPRPQRNSEL
RKGLAEIEEQ MLPSDVIYLP IGNSCHRVKG IRIDECFTFS TKERVPYFLC VEVLDYSVPS
ASKKQRKRRR SKTSRNQSRV FSLRLPFKKT DSDLMVPVDD SPMSSSTSPE SELSFVPSPS
VSSPLPEIEE EKSLETMLDE PLDGEDGDDE KEESKRKSRK SFQEDEGLQR AGEEQQERLG
QWNTSRPRRR SIKEYSSSAS ARSGGQFDSF YSSWFSKKAQ QEAEDEFSAP HASSMQPTQT
IRNDEEDAEA MELAPVETDC TDDNTASTES SEGVLNDIEV EQTQASDVIE DTTKAEAETY
DAVATESATP AANGGIFLSL FSRKPKLEVV NVTSNQHENQ PDDAKEDVPA ESKPAEIEAP
KTATPETACV AAAPAQSAGI FSALFAKKPT DVSVPASIPT ETSVVDKEPS KEEATASSSE
ECNEAKPIVA PAAPVGIFAS IFAKKPAEAT AVAADITVAS ISSLEPSEED VSDDLDAEDA
DGEESESNEA LSSDNDPADR TEASVSSLDR SESGISDSIE AEEADGEDTD SNGGFFSDEE
YAHEPEPSPM TLPAEKPASF VSWFSRKPTA VVVEPAPEKE ENATAVTDTT TSSESPPDSE
TAEASAPVVD DEKDSQDDAL FQQRKRDLSE SLDFADPTAW KKKFDLEDGL TEEEPDLEMT
DVDAVEEDAD EEENDASEDE KPMIVFRERW SEKEARIRRE SPFGGHPGWR LLSVIVKSND
DLRQEQFAAQ LIAQCDRIFR EYSLPLSLRP YNVIATSAKT GLIEAVPDTV SLDSLKRNDP
GYTTLLDFYT RLHGEQGTTG FTRAQRNFAE SLAAYSIVCY VFQIKDRHNG NILVDTDGHV
IHIDFGFLLT NSPGSNWNFE RAPFKLTDEF VELMGGPRSS TFRYFRSLCI RAYLALRRNM
DQIVLLVEMM LVGNADLPCF AGGKKAVIEG LRARLKPGAR TSTCQVFVNQ LIDQSINNWR
TRWYDKYQRA CLGIL
//
