ID A0A0X3RSM4_9ACTN Unreviewed; 484 AA.
AC A0A0X3RSM4;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Peptidase C69 {ECO:0008006|Google:ProtNLM};
GN ORFNames=ADL25_40150 {ECO:0000313|EMBL:KUJ34700.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ34700.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ34700.1}.
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DR EMBL; LMWH01000282; KUJ34700.1; -; Genomic_DNA.
DR RefSeq; WP_059132875.1; NZ_LMWH01000282.1.
DR AlphaFoldDB; A0A0X3RSM4; -.
DR OrthoDB; 9803213at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF10; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000054048}.
FT DOMAIN 19..83
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 112..221
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 243..450
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 484 AA; 51460 MW; B72B34A195D3EDEB CRC64;
MKDTAETVLG LLPRDVAYAD VRVVERTHEL VLVEHEGPGD VMRENSLGVG VRVVIGGQWG
FAATHRLDLK GLTAAVSEAV AQARAADGGA KIALGQPVTT RARWSSPMAV DPFTVPLSGK
LDLLAAAVAE ARTAGPLLRQ IEASMDFFRD DKVFANTEGA LIEQTITESG AGLMAVASDY
DDVQRRSFPQ AVPRSIRGQR GQFATAGYEH IPALRLVEEA ARVGADAVAL LSAPQCPDQN
STLVVTGAQL AMLLHECAGH PMEADRALGS EVSLAGGTYA SPERRGTFRF GSPIVSVHAD
ATIPGALGSY AYDDEGVAAQ RTELVKDGVF TGYLSGRESA ATLGQESSGA ARADGWQRIP
LVRMTNLCLE PGDSSLAEMI DGTKRGVLMD MTKSVSIDDQ RLSFRLGAEA GWEIRDGKLG
RLLKNCTYSG VTPRFWADCD ALGNRDEFQV HGIPSCNKGE PLQVAHIGHG TVPARFRSVQ
IGTR
//
