ID A0A0X3S470_9ACTN Unreviewed; 408 AA.
AC A0A0X3S470;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Beta-ketoacyl synthase {ECO:0000313|EMBL:KUJ38046.1};
GN ORFNames=ADL25_26400 {ECO:0000313|EMBL:KUJ38046.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ38046.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ38046.1}.
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DR EMBL; LMWH01000240; KUJ38046.1; -; Genomic_DNA.
DR RefSeq; WP_059130315.1; NZ_LMWH01000240.1.
DR AlphaFoldDB; A0A0X3S470; -.
DR OrthoDB; 416758at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR CDD; cd00832; CLF; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054048};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 5..406
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 408 AA; 42948 MW; 13AF34CD655EAEA3 CRC64;
MSESGVRVVV TGLGVVAPNG LGAEAYWAAT RKGTSGIGRI SRFVPDRYPA RLAGEIDGFT
AEEHLPGRLL PQTDRMTQLA LVAADWAFRD AAVRPSELPE FEMGVITASS SGGFEFGQRE
LQALWSKGGR YVSAYQSFAW FYAVNSGQIS IRNGMRGPSG VVVSDQAGGL DAVAQARRQI
RKGTRLVMSG AVDASICPWG WVAQMASNRL STTHDPERAY LPFDGSAHGH VPGEGGALLV
LEELEQARAR SADQIYGEIA GYGATLDPRP GSGRPPGLRK AVELALADAG TLPRDIDVVF
ADGAAILELD RIEAEAINGV FGERTVPVTV PKTMTGRLYS GAAPLDLAAA FLAMRDGVIP
PSIGITPSPG HALDLVVGHE RTAPVRSALV IARGHGGFNS ATVVRAVE
//
