ID   A0A0X3VEC9_9ACTN        Unreviewed;       337 AA.
AC   A0A0X3VEC9;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=NADPH:quinone oxidoreductase {ECO:0000313|EMBL:KUL43161.1};
GN   ORFNames=ADL12_08250 {ECO:0000313|EMBL:KUL43161.1};
OS   Streptomyces regalis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL43161.1, ECO:0000313|Proteomes:UP000053923};
RN   [1] {ECO:0000313|Proteomes:UP000053923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL43161.1}.
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DR   EMBL; LLZG01000039; KUL43161.1; -; Genomic_DNA.
DR   RefSeq; WP_062700123.1; NZ_LLZG01000039.1.
DR   AlphaFoldDB; A0A0X3VEC9; -.
DR   OrthoDB; 3727682at2; -.
DR   Proteomes; UP000053923; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05289; MDR_like_2; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR   PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053923}.
FT   DOMAIN          10..330
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   337 AA;  35926 MW;  EB84D281361D36CD CRC64;
     MKAFVVEKYG KDGVRAAEVP EPKVGDRDVL VRVSAASINP LDKLVRNGEL KQVLKYKLPF
     VLGHDVAGVV TRVGSAVHGF KVGDEVYARP RDLRIGTFAE FIAIDMDDVA PKPASLTLHE
     AAAVPLVALA AWQILVDRAH VKPGQKVLIH AGAGGLGSTV IQLAKHLGAT VATTTDTDTE
     KLVRDLGADV VVDYTKEDFR KVLSGYDLAL DAVGGANLEK SLTVLKPGGL AISVVGPPDA
     GFAKQLGAPS FLGLVMNALS RKIRKQAKAL GVRYQFFFMQ ANGSQLRKLG ALYDSGKLRP
     VIDSTFPFDQ TLEAMAHVEQ GRTKAGKVVV SMVPDNV
//