ID   A0A0X3WUF8_9ACTN        Unreviewed;       417 AA.
AC   A0A0X3WUF8;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Threonine aldolase {ECO:0000313|EMBL:KUL60500.1};
GN   ORFNames=ADL30_08290 {ECO:0000313|EMBL:KUL60500.1};
OS   Streptomyces sp. NRRL S-1521.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1609100 {ECO:0000313|EMBL:KUL60500.1, ECO:0000313|Proteomes:UP000053420};
RN   [1] {ECO:0000313|EMBL:KUL60500.1, ECO:0000313|Proteomes:UP000053420}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL S-1521 {ECO:0000313|EMBL:KUL60500.1,
RC   ECO:0000313|Proteomes:UP000053420};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL60500.1}.
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DR   EMBL; LLZK01000086; KUL60500.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0X3WUF8; -.
DR   Proteomes; UP000053420; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053420}.
FT   DOMAIN          92..319
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   417 AA;  44857 MW;  79B20A000C1ED74C CRC64;
     MTSHGATQAS LQSPTGPSAT GDEPEAVGDA PDAAGGEPDA QARRMAAARG ATRTLDRSPL
     HVPLLERFST LAAAAPEAVG PQEPVDLYGN GVVATLEDEV ARLLGKEAAA FFPTGTMAQQ
     VALRCWAGRT GNATVALHPL AHPELHEGGA LSAVSGLRTV WPTTERRLPT ADEVRDFPEP
     FGTLMLELPL RDAGFVLPTW EELEAVVAAA RERDAVVHFD GARLWECPTH FGRPLAEIAD
     LADTVYVSFY KSLEGLSGAA LVGPRTLIEE AKVWRHRYGG QLFQQFPAAV SALLGLRRVL
     PRLPDYVAHA RVVADALREG FAAAGVPWAR VHPERPHTHQ FQVWLPYEPG VLSEASLGQA
     EETKTHLFGR WFPDGPPGLS VTEVTVTEEG LAWTADDVKE AVTEFVRRIP ADGTRRG
//