ID A0A0X3WWT8_9ACTN Unreviewed; 482 AA.
AC A0A0X3WWT8;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:KUL61317.1};
GN ORFNames=ADL30_07495 {ECO:0000313|EMBL:KUL61317.1};
OS Streptomyces sp. NRRL S-1521.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609100 {ECO:0000313|EMBL:KUL61317.1, ECO:0000313|Proteomes:UP000053420};
RN [1] {ECO:0000313|EMBL:KUL61317.1, ECO:0000313|Proteomes:UP000053420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-1521 {ECO:0000313|EMBL:KUL61317.1,
RC ECO:0000313|Proteomes:UP000053420};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL61317.1}.
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DR EMBL; LLZK01000075; KUL61317.1; -; Genomic_DNA.
DR RefSeq; WP_062771327.1; NZ_LLZK01000075.1.
DR AlphaFoldDB; A0A0X3WWT8; -.
DR Proteomes; UP000053420; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000053420};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 24..92
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 84..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 482 AA; 51329 MW; 47D13536F9CD393B CRC64;
MRESWVNLAE RIGSDLHLEL SAAGSRRAVL IRALRDAVRE GRLAPGTRLP PYRSLAADLG
LARNTVADAY AELVAEGWLT ARQGSGTRVA ERAAPPRRTR VPKPAPARPA APAHDLRQGR
PDPGSFPRTA WLTAARRALA AAPNEAFGPG DPRGRIELRR ALADYLARAR GVRADPGRVV
VCSGFAHALR LLFAGSDGAG GAVLRGPLAV ESYGLGFHRE ILRGAGVRTV PLGLDEQGAR
VEELPHAGRG GRVRGVLLTP AHQFPTGGPL HPSRRAAVVD WARAGGGLLL EDDYDGEFRY
DREPVGAVQG LDPEQVVYLG SVSKSLSPAV RLGWMVLPER LVEGVVAAKG EREAWASVLD
QLTLAEFIAS GQYDRHIRRM RQRYRRRRDL LVSALAERAP HITATGVAAG LHAVLRLPPG
TEASAAKAAA WQGVAVEGLA EFRHPRATMA AADGLVVGYS TPAEHAYGAA VDALVRALPP
GP
//
