ID A0A0X3X2V1_9ACTN Unreviewed; 743 AA.
AC A0A0X3X2V1;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ADL30_03950 {ECO:0000313|EMBL:KUL63428.1};
OS Streptomyces sp. NRRL S-1521.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609100 {ECO:0000313|EMBL:KUL63428.1, ECO:0000313|Proteomes:UP000053420};
RN [1] {ECO:0000313|EMBL:KUL63428.1, ECO:0000313|Proteomes:UP000053420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-1521 {ECO:0000313|EMBL:KUL63428.1,
RC ECO:0000313|Proteomes:UP000053420};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL63428.1}.
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DR EMBL; LLZK01000014; KUL63428.1; -; Genomic_DNA.
DR RefSeq; WP_062770257.1; NZ_LLZK01000014.1.
DR AlphaFoldDB; A0A0X3X2V1; -.
DR Proteomes; UP000053420; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053420};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 558..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 667..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 198..330
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 724..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 76271 MW; 32CDA765373D4078 CRC64;
MAAFLYRMGR TAFRRRWLVT LLWVVILGCV GLGAAKAPAA GDDGTSFMPG IEAQRAFDLI
GERFPGSDAN GANARVVFIA PDGEKVTAEE NRAAIDELVS TVADDAQVDS AVDPFKAHAV
SEDASTAYAT VDYEVKADDL SDASKDSLEK AVDQAREAGL TVEVGGTALA SQPAAGGSAE
AIGIALAAVV LLITFGSLAA AGLPLLTAVI GVGVSMCAIL ALGSALGLSM TTGTLASMLG
LAVGIDYALF VVSRYREERT HGHDPREAAG LAVGAAGSAV VFAGLTVIIA LAGLAVVGVP
MLTKMGVCAA GAVAVGVLVA LTLVPALLGM WPNAVLSRKV RKPGKRGGGR RFGIAGSGGT
RWARFVLRRP VAVLLLGVAG LGALALPAAQ LEMGMPGDEA KPASTTERRA YDALAAGFGA
GFNGPLTIVA DVKGAADPRA AAATMAERIK DTEGVVSVTS PRLNEAGDAA LFSAVPAAGP
NEEATKGIVR TIRAERPGLE AETGTTFEVT GSTAMNIDVA QALQEALVPY LSVIVLLSLL
LLLIVFRSVL VPVKAALGFL LSVLASLGAV VAVFQWGWGA GLLGVEQTGP IMSLMPIFLV
GIVFGLAMDY EVFLVARMRE AYVHGERPGQ AVVSGFRHSA RVVVAAAVIM MAVFSGFIAS
GESMIKTIGF GLAVAVLFDA FVVRMALVPA VLALLGDKAW WLPRWLDKAL PRVDVEGSAL
TSQREASAAT GVETHTREPA RAA
//
