ID A0A0X8HHE3_9GAMM Unreviewed; 786 AA.
AC A0A0X8HHE3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cyclic di-GMP phosphodiesterase Gmr {ECO:0000313|EMBL:AMD02645.1};
DE EC=3.1.4.52 {ECO:0000313|EMBL:AMD02645.1};
GN Name=gmr_8 {ECO:0000313|EMBL:AMD02645.1};
GN ORFNames=LOKO_03605 {ECO:0000313|EMBL:AMD02645.1};
OS Halomonas chromatireducens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=507626 {ECO:0000313|EMBL:AMD02645.1, ECO:0000313|Proteomes:UP000063387};
RN [1] {ECO:0000313|EMBL:AMD02645.1, ECO:0000313|Proteomes:UP000063387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD02645.1,
RC ECO:0000313|Proteomes:UP000063387};
RX PubMed=26988058;
RA Sharko F.S., Shapovalova A.A., Tsygankova S.V., Komova A.V.,
RA Boulygina E.S., Teslyuk A.B., Gotovtsev P.M., Namsaraev Z.B.,
RA Khijniak T.V., Nedoluzhko A.V., Vasilov R.G.;
RT "Draft Genome Sequence of 'Halomonas chromatireducens' Strain AGD 8-3, a
RT Haloalkaliphilic Chromate- and Selenite-Reducing Gammaproteobacterium.";
RL Genome Announc. 4:0-0(2016).
RN [2] {ECO:0000313|EMBL:AMD02645.1, ECO:0000313|Proteomes:UP000063387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AGD 8-3 {ECO:0000313|EMBL:AMD02645.1,
RC ECO:0000313|Proteomes:UP000063387};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP014226; AMD02645.1; -; Genomic_DNA.
DR RefSeq; WP_066452016.1; NZ_CP014226.1.
DR AlphaFoldDB; A0A0X8HHE3; -.
DR STRING; 507626.LOKO_03605; -.
DR KEGG; hco:LOKO_03605; -.
DR PATRIC; fig|507626.3.peg.3606; -.
DR OrthoDB; 8553030at2; -.
DR Proteomes; UP000063387; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071111; F:cyclic-guanylate-specific phosphodiesterase activity; IEA:UniProtKB-EC.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AMD02645.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000063387};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 223..271
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 292..345
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 377..516
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 525..776
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 786 AA; 87926 MW; BEF7790A6FBFDFC1 CRC64;
MPSPPPAESR ELFGASLPVS TQCRQLVHEQ VRLLYERLWQ PVLASVLGAC LLVAAMWPLL
PATLLIGWLV VLVFVSSGRL GLAWYYHRQP ASRRHQRCWL RRFAWGAGIA GAVWGAAGLL
MFTMEHQGQL AALTIVLTGV AAGGMTTLSS VWWVAPVFIL PALLPLLGQL LFQGSPFSWL
LSAMVVLFLG LLLTVSRRLH HIISDNIALR LAVTSRESQL RESESRYRAI FRHTPLGVMH
FDGEGRVVDF NEKCLEILGT TWERLQGFNL LEQAEDKRVS GAVRQALVSG TGYYEGTYRA
ILSGKQTPLR AFYNALRNEA GEIVGGVALI EDFTERKRAE ETIHRQAYFD PLTELPNRRL
LIETLASTIR DRRDDGRLGL VMFLDLDRFK MINDSLGHSV GDELLRQLSK RLLVCMRDGD
MAARLSGDEF VVLVPALSGD REAELVRAEQ MARELLSSLR KVYDLAGQRI SVTPSIGYTL
FPLTVDEDVG DVLRHADTAM YQAKVKGRAQ VCGYEPSMQT QITWRLEMEQ ALRSALTEDQ
LFAQYQPQLD QNGRIFGVEA LMRWQHPVHG WISPEVFIAI AEESDLIVEL ETWMLDSCCE
LLARLPAEML PRLSVNISVR HFTQPGFVEG VTWVLGTHGI DPSRLTIELT ESIMIDGLGE
AVDRMHQLKR LGLNLALDDF GTGFSSLTYL KCLPLDELKI DRSFVSDLDS DSNDAAIVET
ILAMAQHLGI EVVAEGVENE AQLDFLLARG CRRFQGYHFH RPMAIELLEQ LLSRSQESAG
SGQITD
//
