ID A0A100IT63_ASPNG Unreviewed; 343 AA.
AC A0A100IT63;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc-binding oxidoreductase CipB {ECO:0000313|EMBL:GAQ46631.1};
GN ORFNames=ABL_09292 {ECO:0000313|EMBL:GAQ46631.1};
OS Aspergillus niger.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=5061 {ECO:0000313|EMBL:GAQ46631.1, ECO:0000313|Proteomes:UP000068243};
RN [1] {ECO:0000313|Proteomes:UP000068243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000068243};
RX PubMed=26893421; DOI=10.1128/genomeA.01700-15;
RA Gong W., Cheng Z., Zhang H., Liu L., Gao P., Wang L.;
RT "Draft genome sequence of Aspergillus niger strain An76.";
RL Genome Announc. 4:E0170015-E0170015(2016).
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAQ46631.1}.
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DR EMBL; BCMY01000022; GAQ46631.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A100IT63; -.
DR VEuPathDB; FungiDB:An16g01630; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1165964; -.
DR VEuPathDB; FungiDB:ATCC64974_72750; -.
DR VEuPathDB; FungiDB:M747DRAFT_297352; -.
DR OMA; WITAPTE; -.
DR Proteomes; UP000068243; Unassembled WGS sequence.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR CDD; cd08249; enoyl_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 15..341
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 343 AA; 36682 MW; D5DA2A6EBA397B02 CRC64;
MTHNKAAWIT APTEHPFTIQ DAPYPTPGPG EIVIKNSAIS INPADWKIQI YGAPWLKNWP
FVLGTDVAGV VVDVGPDVVR FTRGQRVVAY CHCLGTGNPA NSGFQLYTLV KETTVAAIPD
SISFEEASVL PQAISTAAAG LFLKESLDLP IPPPTGVKPT GKSILIWGGA SSVGATTIQL
AVAAGLTVIT TASAHNHELV KSLGATAVFD YKSPTVVDDV VNALTNTEFI GVYDAVSEPA
SLELVRVVLD KLKADVRTIC VIPYDKPTER FAPIFISSNF LTFDSNKHVA EGIWRDFVFK
ALETGRLQPK PDPEVVGKGL EKVQEAVDTL KRGVSAKKIV VTL
//
