ID A0A101E6Z3_9FIRM Unreviewed; 445 AA.
AC A0A101E6Z3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Radical SAM superfamily enzyme,PDZ domain-containing protein {ECO:0000313|EMBL:KUK10475.1};
GN ORFNames=XD50_1227 {ECO:0000313|EMBL:KUK10475.1};
OS Clostridia bacterium 41_269.
OC Bacteria; Bacillota; Clostridia.
OX NCBI_TaxID=1635275 {ECO:0000313|EMBL:KUK10475.1, ECO:0000313|Proteomes:UP000053409};
RN [1] {ECO:0000313|Proteomes:UP000053409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA Andersen G.L., Banfield J.F.;
RT "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT Other Microbial Community Members in Biogeochemical Transformations in Oil
RT Reservoirs.";
RL MBio 7:e01669-15(2015).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUK10475.1}.
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DR EMBL; LGEZ01000013; KUK10475.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101E6Z3; -.
DR STRING; 1635275.XD50_1227; -.
DR Proteomes; UP000053409; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd00136; PDZ; 1.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007549; DUF512.
DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04459; DUF512; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 10..233
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
FT DOMAIN 219..273
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 445 AA; 49798 MW; 3022AB398484A646 CRC64;
MEKIEEIIVS SVGLHNTIPL TSRCNLSCIY CSHRGNPPGI KVYRIPDLTV DDVSFLLDFV
DSKRKVVIGE SATRIVEGEP LLNPQFKDIL KVIRKKLPET IIQITTNGTL IDKNTAAFLK
MLKPLEFVVS VNSPGVLGTI REEIWYKITK ALEYLSSAEI AFGCSLVPLL GVTGWEEIES
TIKAVAETNA LYLRVIPPGV TKYSPLGVRH SFNEAAAKLK TLISGKKSSF GLPIVLEPGE
IDNLKAYVEG VIYKSPAFKG GLRAGDEIRS INGSEPWSRV DAFQKLYALE NPEVEYRRGR
NILRSIIPKR KNSSPGVIMF YDFDPQRAFR MKEQLLANEG KTLILTSQAG FKRVKLALKK
LGFSCSVEVR AVRSRFFGGN ISCSGLLTVR DIIEELKYMR KEAVDKFNYQ LIMIPNEIFD
VKGMDLEGRY FSEITGFIDV PVMLM
//
