ID   A0A101IYB7_9EURY        Unreviewed;      1372 AA.
AC   A0A101IYB7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Heat repeat-containing PBS lyase {ECO:0000313|EMBL:KUL03582.1};
GN   ORFNames=XE11_1192 {ECO:0000313|EMBL:KUL03582.1};
OS   Methanomicrobiales archaeon 53_19.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales.
OX   NCBI_TaxID=1641394 {ECO:0000313|EMBL:KUL03582.1, ECO:0000313|Proteomes:UP000054757};
RN   [1] {ECO:0000313|Proteomes:UP000054757}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=26787827; DOI=10.1128/mbio.01669-15;
RA   Hu P., Tom L., Singh A., Thomas B.C., Baker B.J., Piceno Y.M.,
RA   Andersen G.L., Banfield J.F.;
RT   "Genome-Resolved Metagenomic Analysis Reveals Roles for Candidate Phyla and
RT   Other Microbial Community Members in Biogeochemical Transformations in Oil
RT   Reservoirs.";
RL   MBio 7:e01669-15(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL03582.1}.
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DR   EMBL; LGHF01000017; KUL03582.1; -; Genomic_DNA.
DR   PATRIC; fig|1641394.3.peg.334; -.
DR   Proteomes; UP000054757; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 6.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR004155; PBS_lyase_HEAT.
DR   PANTHER; PTHR12697:SF5; DEOXYHYPUSINE HYDROXYLASE; 1.
DR   PANTHER; PTHR12697; PBS LYASE HEAT-LIKE PROTEIN; 1.
DR   Pfam; PF13646; HEAT_2; 5.
DR   SMART; SM00567; EZ_HEAT; 16.
DR   SUPFAM; SSF48371; ARM repeat; 3.
DR   PROSITE; PS50077; HEAT_REPEAT; 2.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:KUL03582.1}.
FT   REGION          515..552
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1194..1372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1270..1293
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1327..1342
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1353..1372
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1372 AA;  150051 MW;  C0503EF8DEB983A9 CRC64;
     MVFNRLFGVN IQNLAERGKF DRISAMINQD DPEVKLEAVS VLAAHGGVAY EHLANTLSAL
     ISPLEQTQLV REVYFMLADD PEALVRFILV SPENVRTILR KYIISEGRPD LSTLYSLSRR
     RDPELRRAAI ATADTLGKEG FDIILSGLFD RDPDVAAEAA SILERRDLVP DTPKERAQYL
     YVRKKWNELV HIGKAGTPIL LRLLKSGDQP TRRAVIKALG KGHNPEMLLV LHRYLGDPDP
     LIVGDVVAAI AEIGGPEAES TLEKCLNARY PLIRMEASWG LQRMGWKPKN EQQRIMSLLA
     REDWAGLAAM GKNAIPALIN ALRETHSAVR AGATETLRNI GPVAIHSLRQ VSTSTDPNLA
     KVARNALAEI EKKNRQLMVE SHGKPADNKK YQSELSASLK ARESFDKVRK KSGQPQAVVR
     EEVVKPPAPD LSKKKYADEL AASVKAQQEF RKQVPQKPMP ATVKPPSVPE EAKKDLEVND
     IILKGLNEAL RKMYGDIGPR VPIGDEDELK PVKKTDEDVA LTESSIKAEP VQEPLPIPKK
     EEEEEESEEA DNFDKLVASL SDRDTNIRIS ACYALRIYRE RAVSPLIRAL HDPIASVKVA
     AIESLGEIAD PEAKEALMDC IRDDEPEVQI AAVTALGSYM DDDVVRMLVT LLGHDHYRII
     TAASDALVKI HYMALPALAG ALNHTHMRIR TNAAATLGKM EDQDVVPILM KYLEDPSEEM
     RIAIAKALAR VGYPALRPLS EMVVGGSRLQ KLTALDTLGR MSEDEATAAI RPALGDPDQG
     IRIFALQMIR KRESLALWRR AWAEQLGGVV PKPKGIPRLK KDDKELYDQS GGEEDVQSLI
     QGLKDSNRNV QFAAAMKLTV MGRPAIEELL KAVKGESPEI RALAEEVIGE MRDVAVEPLL
     DALYDESSVV RAIAARNLGR IGAKKGFDSL ERAFETEQET DVRAIIVEAL GYIGTGEVVP
     TLKRALHDRD EEVRLVAARA LGYINDNSAV EALISALDDT DTRIAEAALT ALKDPDGTPQ
     EHLVQAMRDA GGFRNKSISS ALTSIGWEPE TEEEEVCFLI SENRWFDIEK MGVCAIKPIV
     DTLQGGTLEE RIEGIKTISH IGGPEAVNAL IPLLSDEHIM VRKKAEYALI DLGELSVEPL
     NALIGDEKGP LDKTIQRIQN QIESKRLSGG GPAGIGETDF DIAETGTIES ILSGTAVSED
     SYPAPGSSDE GVPEYGDAEA PEIPDDASDE THGTTPEEMP EDMSISAADL SPEADEYPEP
     SPEDAATETP ESIPFEDDDG IPSVDDISFE MDEPLELFDT PPIPEAADPL DHPSSAGDDG
     IPSLDESSFQ KEVSSDSTEP PSPPSEAADE ASSPGVAEEK RKRSPEHERD EG
//