ID   A0A101JHQ7_9ACTN        Unreviewed;      1021 AA.
AC   A0A101JHQ7;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Lantibiotic biosynthesis protein dehydration domain-containing protein {ECO:0000259|Pfam:PF13575};
GN   ORFNames=ADL12_32425 {ECO:0000313|EMBL:KUL26661.1};
OS   Streptomyces regalis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL26661.1, ECO:0000313|Proteomes:UP000053923};
RN   [1] {ECO:0000313|Proteomes:UP000053923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL26661.1}.
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DR   EMBL; LLZG01000361; KUL26661.1; -; Genomic_DNA.
DR   RefSeq; WP_062708549.1; NZ_LLZG01000361.1.
DR   AlphaFoldDB; A0A101JHQ7; -.
DR   OrthoDB; 9148343at2; -.
DR   Proteomes; UP000053923; Unassembled WGS sequence.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR   CDD; cd04792; LanM-like; 1.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR025410; Lant_dehyd.
DR   InterPro; IPR017146; Lanti_2_LanM.
DR   NCBIfam; TIGR03897; lanti_2_LanM; 1.
DR   Pfam; PF13575; DUF4135; 1.
DR   Pfam; PF05147; LANC_like; 1.
DR   PIRSF; PIRSF037228; Lant_mod_RumM; 1.
DR   PRINTS; PR01950; LANCSUPER.
DR   SMART; SM01260; LANC_like; 1.
DR   SUPFAM; SSF158745; LanC-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053923}.
FT   DOMAIN          162..531
FT                   /note="Lantibiotic biosynthesis protein dehydration"
FT                   /evidence="ECO:0000259|Pfam:PF13575"
SQ   SEQUENCE   1021 AA;  110513 MW;  5965A08923D65786 CRC64;
     MTSPALYYPE FDSVEIEETI SPLAEFDREI LSAVHKGGAH RAASVGEARA SAAEWADRSE
     DYPFQRVIRT MAASLAEREP ISSFLDSPAV WDLFDDPRTA LHQILGRAES RLRETCTRAL
     VAAVNHAREK GLLTGTDPAE RYASFVERAT RTSFAEAGGV DFPVLHGVVP TILRNEADSI
     MEMCCRLGAD RRAIAAAFGI AETDRIVSLG LSEGDTHHHG RSVSVVRFAS GKHLVYKPRD
     VSCEAAYERL AGELNRRLGT RLVAAAVLKR DGYGYVEFID TEDVSDRSGD FMEASGELAA
     VLYLLNARDM HFENIVPTRR GPVPIDLETI LHPARIHRGP TPEAPGNAFE TIAQSVYGIG
     ILPLVMVGKK ATAGHVDLGF LGDQGQGNSP FKSMQFEEPF TDRVRLVLRE QEAQPRRTVV
     STLTEDEVHA LGERMTDGFT RVFRAVLEDR ETFAGLLRET VADVRVRYVH NPTVLYAQTM
     RMTSGARALA DHDVYAALLK RVAIPSKTSD RQIVRSEMRQ LAERDIPYFT VASTSVVLQD
     GDGAEVASFP ESPLERALAK VRAMTEFDLQ EQLRLIHSAF ACRFPDNHLA AALPAAPDTE
     RAGTAPGAGS DPCADGTAAA LAARLCDRLI ASSLPDKYAH LPRTWIGPLA SAQVGRPWPP
     TVLGYDLYTG RVGPALALAA AGRVLGRDDY REQATQIFST TADILARERY EKRSIEQAGF
     AGYTGMAGIL FALTAAGRLL DRDDWVSAAQ GAVPLVLGQL RALPQAELPL DVISGVAGVL
     SCVAEIGGEH GAQAVAELTS LLTAGLPRDG REPAGPARAA LEQSGYAHGI AGLLHVLCRA
     HPLLPADGRP AVESAAAYLA GRLDGFFDRA ENNWFSNVAT PTSFSTGWCH GATGISLALD
     AYAGLSGDPD AARKRDMAVG NLLRHGFGRN LTWCHGDLGN HDALTALAAR TQDPVLREAR
     TAVEDRWLRP EVFERKLADT RSRYAHTSSL MVGWAGVVLH LVHRLDPTVR VSPVTLTVEG
     R
//