ID A0A101JJ54_9ACTN Unreviewed; 717 AA.
AC A0A101JJ54;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ADL15_33525 {ECO:0000313|EMBL:KUL27763.1};
OS Actinoplanes awajinensis subsp. mycoplanecinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL27763.1, ECO:0000313|Proteomes:UP000053244};
RN [1] {ECO:0000313|EMBL:KUL27763.1, ECO:0000313|Proteomes:UP000053244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL27763.1,
RC ECO:0000313|Proteomes:UP000053244};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL27763.1}.
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DR EMBL; LLZH01000294; KUL27763.1; -; Genomic_DNA.
DR RefSeq; WP_067699543.1; NZ_LLZH01000294.1.
DR AlphaFoldDB; A0A101JJ54; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000053244; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053244};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 657..682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 217..343
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 552..680
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 104..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 76367 MW; 8E3E16185D1D61AB CRC64;
MAVNVAPTKE TPPGPVPSRW VPWLVIGLWV ALAAVMVPLS GKLSSVTKDR AVDALPASAD
STKVAALEDK LPGGEENTFV FVYHRAGGVT ADDRASVERH YNTMATRYPP KVTPPAGEND
EGPPTQISND GKAMMFTLNV STSYGEPAVL TGPMRDIAKD RPAGLDLDVT GPAGIDADMD
AVFDGIDVQV FLTTVIVVTI LLILTYRSPV LWFIPLVAVG VAALTSMATV YLLVKGFGLV
INSQNSALLT ILVFGVGTDY ALLLIARYRE ALHQHENVRV AMLHALRGAA PAIVASAATV
IGGLLCLLAA DLNETRGLGP IGAAGILCAL VAMLTLFPAV LVVLGRRIFW PAIPRFGTAM
QQKPGLWGRL GAAISRRRWV ATLASLGVLG VLTIGLTGNT SILREQDQFL STPESVTGFT
VLREHFPELG GQPMTVFTRA AYQEQVLDVV KHTPGVAQVE TGETKEGWVD ISVFPKDAPD
TTAEYDTIRR VRAAVHTVNG AEALVGGPSA EHLDTDVTTR RDQKVVIPLV LAVVLIILGL
LLRAIVAPLM LMATVIVSFA AAFGGSVFIF EMILGFKGID YSVPLLAFMF LVALGVDYNI
FLTHRAREET VRLGTRDGIL KALSATGGVI TSAGLVLAAT FAVLVSLPLV MLVELGFLVA
FGVLLDALLV RSVLVPALTL LIGRRIWWPS RLSRPAAETP PTARHSLADD QEPVLQR
//
