ID A0A101JRS0_9ACTN Unreviewed; 704 AA.
AC A0A101JRS0;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Bi-functional transferase/deacetylase {ECO:0000313|EMBL:KUL31251.1};
GN ORFNames=ADL15_22630 {ECO:0000313|EMBL:KUL31251.1};
OS Actinoplanes awajinensis subsp. mycoplanecinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=135947 {ECO:0000313|EMBL:KUL31251.1, ECO:0000313|Proteomes:UP000053244};
RN [1] {ECO:0000313|EMBL:KUL31251.1, ECO:0000313|Proteomes:UP000053244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16712 {ECO:0000313|EMBL:KUL31251.1,
RC ECO:0000313|Proteomes:UP000053244};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL31251.1}.
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DR EMBL; LLZH01000223; KUL31251.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101JRS0; -.
DR Proteomes; UP000053244; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06423; CESA_like; 1.
DR Gene3D; 3.20.20.370; Glycoside hydrolase/deacetylase; 1.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR002509; NODB_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43630; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR PANTHER; PTHR43630:SF1; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR Pfam; PF13641; Glyco_tranf_2_3; 1.
DR Pfam; PF01522; Polysacc_deac_1; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS51677; NODB; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053244};
KW Transferase {ECO:0000313|EMBL:KUL31251.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 306..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 591..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..686
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 80..268
FT /note="NodB homology"
FT /evidence="ECO:0000259|PROSITE:PS51677"
SQ SEQUENCE 704 AA; 76085 MW; 752E5D513B3BD8C7 CRC64;
MPKEPRRIHR PRPRWIVFAV LISLFASILL VNGLVQGEFT QDGATAATTQ TSQVPAEALT
GGPIIATDGT TTTSVSVPDK QIVLTFDDGP DPEYTPEILE VLAEYGVTGT FFMIGSQISE
YPDLVRQVAE AGNEIGIHTY THPELSGASE WRRTVEMRET QLALAGAAGV TSVIFRPPYS
STVAALDDDS WAVMQDMGEQ GYLTVVNDLD SRDWEQDVTV DDIVEAVTPD DGAGAVLLFH
DGGGDRSLTA DALREVIPAL LAEGYTFTTV AAVSGMATVN PDATAGEQAL GLGLVSAVQI
ATHVSAWFSG LLLIFGVLTV ARLLFMLVLG RRHARRGRSG HRWGPAFTEP VTVIVPAYNE
KECIADTLGS LVASTHPVRI IVVDDGSTDG TAEIAEALGL PGVTVLRQPN SGKPAALNAG
IAAADTDVVV MMDGDTVFEP DTVRLLVQPF ADPAIGAVAG NAKIANRTGM IALWQHIEYV
VGFSVDRRAQ DVMGCMATVP GAVGAFRTEA LRQVDGLSDD TLAEDTDLTM AIVRAGWRVV
YEERARAWTE APATVGQLWR QRYRWSYGTM QAMWKHRRAV VEKGSFGRRG LLNLALFQTL
MPLLSPLIDV FLIYGLLFLN PAETVLAWFT VLAVQVLSTV YAFRLDAESL RPIWRVPLQQ
FVYRQLMYLV LIQSTLAALG GIRLGWQKLQ RAGGLSALLG ARAR
//
