ID   A0A101KQR3_RHILI        Unreviewed;       440 AA.
AC   A0A101KQR3;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Homoserine dehydrogenase {ECO:0000313|EMBL:KUM25172.1};
GN   ORFNames=AU467_27185 {ECO:0000313|EMBL:KUM25172.1};
OS   Rhizobium loti (Mesorhizobium loti).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=381 {ECO:0000313|EMBL:KUM25172.1, ECO:0000313|Proteomes:UP000053176};
RN   [1] {ECO:0000313|EMBL:KUM25172.1, ECO:0000313|Proteomes:UP000053176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UFLA 01-765 {ECO:0000313|EMBL:KUM25172.1,
RC   ECO:0000313|Proteomes:UP000053176};
RA   Rangel W.M., Thijs S., Longatti S.M., Moreira F.M., Weyens N.,
RA   Vangronsveld J., Van Hamme J.D., Bottos E.M., Rineau F.;
RT   "Draft genome sequence of Mesorhizobium sp. UFLA 01-765, a multitolerant
RT   efficient symbiont and plant-growth promoting strain isolated from Zn-
RT   mining soil using Leucaena leucocephala as a trap plant.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUM25172.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LPWA01000121; KUM25172.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A101KQR3; -.
DR   OrthoDB; 9777844at2; -.
DR   Proteomes; UP000053176; Unassembled WGS sequence.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd11616; SAF_DH_OX_like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR005106; Asp/hSer_DH_NAD-bd.
DR   InterPro; IPR048423; DRL_cat.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR37850:SF2; SAF DOMAIN PROTEIN; 1.
DR   PANTHER; PTHR37850; STRU PROTEIN; 1.
DR   Pfam; PF21135; DRL_cat; 1.
DR   Pfam; PF03447; NAD_binding_3; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          27..155
FT                   /note="Aspartate/homoserine dehydrogenase NAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03447"
FT   DOMAIN          162..325
FT                   /note="Oxidoreductase DRL-like catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF21135"
SQ   SEQUENCE   440 AA;  46844 MW;  F2AFA33715A0D438 CRC64;
     MSHPQFAAEL LQRAEKQGPI TIGLAGAGQM GTDIVVQVAL MPGMRIGAIS EVRPQAAIDA
     ALLAGHDRSD IVQAPNAAAI DRAIEAGKIA ITEDLHALAA AGRIDVIIDA TGNPNIGTLF
     ALEVMKNGKH IVMLNVEADI TIGRFLKEEA RKAGVVYTGA AGDEPACTLE IIGFAKSLGF
     NIIAAGKGKN NPLKFDAVPA DYEKEAAERN MNARMLVEFV DGSKTAIEMV AIANATGLVP
     DVPGMHGPTA TLEELASVLC PREDGGVLHR KGVVDYSIGK GVAPGVFCII ETRHPRVLER
     MIDLKVGKGP YFTIFRPYHL TSLEVPLSAA RAVVYKRADM EPLDHPVAEA VAVAKTNLGA
     GQSLGMIGEN DYRGFAMTWE DARAKRALPL GLAERAKVVK PVKAGDFLTY ENCVPDDSMV
     ITQIRRRLDQ SDGRFVTNAA
//