ID A0A101NKL2_9ACTN Unreviewed; 511 AA.
AC A0A101NKL2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Calcineurin-like phosphoesterase domain-containing protein {ECO:0000259|Pfam:PF00149};
GN ORFNames=AQI88_19860 {ECO:0000313|EMBL:KUM95068.1};
OS Streptomyces cellostaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM95068.1, ECO:0000313|Proteomes:UP000054241};
RN [1] {ECO:0000313|EMBL:KUM95068.1, ECO:0000313|Proteomes:UP000054241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM95068.1,
RC ECO:0000313|Proteomes:UP000054241};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT for the species Streptomyces cellostaticus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM95068.1}.
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DR EMBL; LMWL01000034; KUM95068.1; -; Genomic_DNA.
DR RefSeq; WP_067000832.1; NZ_KQ948023.1.
DR AlphaFoldDB; A0A101NKL2; -.
DR STRING; 67285.AQI88_19860; -.
DR OrthoDB; 5241348at2; -.
DR Proteomes; UP000054241; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR31302:SF0; TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN; 1.
DR PANTHER; PTHR31302; TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054241};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 254..421
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT REGION 487..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 511 AA; 54319 MW; 7117D00A735D0133 CRC64;
MARVRVPVAA LRSRRTPSAP PALPALEPAA RPRPWLSALG LTAVVLVGAW LGLLIVGNVR
APVGPMNTTM ALRPSLTGGT KINVSPLGAL TLDSHVAPVR LDVNVDQLDP LRSQALVDHP
ERLSGLQDEV ARDVEHGTLD LAVRSSVAVV SGATALGLAV YRRPRRALAA GGLALTLLAA
SGATAYATWN PKSVLEPKFS GLLSSAPSLV GNARNIVTEF DVYQKELARL VTNVTKLYDV
TSTLPAYQPD PATLRVLHVS DIHLNPASWK IIASLVEQYK VNVIVDSGDT MDHGTAAENG
FLDPVEDLGA PYVWVRGNHD SRVTQRYLER MKNVHVLDDG RAQTIAGLRF AGIGDPQFTP
DRSVTPGGNA AEQLAGDRLA TALRDQRAAG TPVDVAIAHE PSAARETDGE VPLVLAGHLH
HEGTEVMKYG TRLRIEGSTG GSGLRAVEGK HPDPIEASIL YFDRDSRRLQ AWDEIKLGGL
GLTTAEVSRH LPKENQPGAT PAPSSPSPSR S
//
