ID A0A101NR97_9ACTN Unreviewed; 458 AA.
AC A0A101NR97;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cysteine desulfurase {ECO:0000313|EMBL:KUM97737.1};
GN ORFNames=AQI88_05810 {ECO:0000313|EMBL:KUM97737.1};
OS Streptomyces cellostaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67285 {ECO:0000313|EMBL:KUM97737.1, ECO:0000313|Proteomes:UP000054241};
RN [1] {ECO:0000313|EMBL:KUM97737.1, ECO:0000313|Proteomes:UP000054241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40189 {ECO:0000313|EMBL:KUM97737.1,
RC ECO:0000313|Proteomes:UP000054241};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces cellostaticus DSM 40189, type strain
RT for the species Streptomyces cellostaticus.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- SIMILARITY: Belongs to the sulfur carrier protein TusA family.
CC {ECO:0000256|ARBA:ARBA00008984}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM97737.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMWL01000008; KUM97737.1; -; Genomic_DNA.
DR RefSeq; WP_066992863.1; NZ_KQ948016.1.
DR AlphaFoldDB; A0A101NR97; -.
DR STRING; 67285.AQI88_05810; -.
DR OrthoDB; 9808002at2; -.
DR Proteomes; UP000054241; Unassembled WGS sequence.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR CDD; cd00291; SirA_YedF_YeeD; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.30.110.40; TusA-like domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR001455; TusA-like.
DR InterPro; IPR036868; TusA-like_sf.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR Pfam; PF01206; TusA; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF64307; SirA-like; 1.
DR PROSITE; PS01148; UPF0033; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000054241}.
FT DOMAIN 389..413
FT /note="UPF0033"
FT /evidence="ECO:0000259|PROSITE:PS01148"
SQ SEQUENCE 458 AA; 48004 MW; E5AD2D6A316F09BC CRC64;
MSYFDAASAA PLHPVARQAL LASLDEGWAD PARLYREGRK ARMLLDAARE AVAEAVGCRA
DEVVFTSSGT RAVHTGVAGA LAGRRRVGRH LIVSAVEHSS VLHSAEAFEA EGGAVSRVAV
NRAGAVDASA YAAALRQDTA LACLQSANHE VGTVQPVAQV AEVCRAAGVP LLVDAAQSLG
WGPVEGDWSL LAASAHKWGG PSGVGLLVVR KGVRFAAQGP VDERESGRAP GFENLPAIVA
AVASLRAVRA EAAEEGVRLR ELTERIRVRV PELVPDVEVV GDAERRLPGI VTFSCLYVDG
EALLHELDRE GFSVSSGSSC TSSTLTPSHV LKAMGVLSEG NVRVSLPPGV AEEDVERFLD
VLPGTVAGVR EKLGAPAPAT VVQAQELVVD SLGKRCPIPV IELAKVFGEV PVGGTVRVLS
DDEAARLDIP AWCEMRGQEY VGEEPAERGT AYVVRRVS
//
