ID A0A101NUT3_9ACTN Unreviewed; 739 AA.
AC A0A101NUT3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=AQI95_37910 {ECO:0000313|EMBL:KUM99735.1};
OS Streptomyces yokosukanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67386 {ECO:0000313|EMBL:KUM99735.1, ECO:0000313|Proteomes:UP000053127};
RN [1] {ECO:0000313|EMBL:KUM99735.1, ECO:0000313|Proteomes:UP000053127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40224 {ECO:0000313|EMBL:KUM99735.1,
RC ECO:0000313|Proteomes:UP000053127};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces yokosukanensis DSM 40224, type
RT strain for the species Streptomyces yokosukanensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUM99735.1}.
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DR EMBL; LMWN01000061; KUM99735.1; -; Genomic_DNA.
DR RefSeq; WP_067134951.1; NZ_KQ948227.1.
DR AlphaFoldDB; A0A101NUT3; -.
DR STRING; 67386.AQI95_37910; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000053127; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053127};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 571..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..636
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 657..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..714
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..387
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 420..729
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 739 AA; 78897 MW; D53E21152F67F96A CRC64;
MNSLTVRIAR WSAGHPWRAL VGWLLFVALC LGVGSAVGTD SAKTADYRVG EAGRAETMAA
EGHLERLSTE QILISALPRS RPRPDGGTSV GALDEGPAAA AAHELTARMR RLPEVAQVAD
PVRSSDGRVL MVEVSLKGEE LDADAKVGAL VAQTRAVQRA YPGLLVQETG SASVSKGVDQ
QRDDDLALSE KISLPVTLVT LLIVFGSLTM AAVPLLLALS SIAAAVGLAM VASHLTPDTG
VGTNVILMIG LAVGVDYTLF HLKREREERA RCGGRLGTEA LVELAAATSG RAVVVSGLAV
VASTATLYLA SDVIFSSLAT GTVVVVLVAV ASSLTALPAL LTVLGRRSER RARRAAERGK
PSRRLRGGDG GRFWSALLRP AARHPLATLC CSLLALLALV LPLTGLKITE MSRDTHSRAI
PAMRVYDRLN AEFPERRVTH QVVVQAPASR AAQVDRELRA LGRRAAADPL FTDYARIRTA
ADRRTSTLEL RVPYLGDSPQ AVASLEHLRR DYLPATVGKV TGARYGVSGD VARYQDYPAH
QNGRLPLVLG ALLLVTFLMT LYAFRSVVLG LIGVVLNLLS AAAALGLLVL VFQHTWAEGL
LDFRSTGSIG SRVPLFLFVI LFGLSMDYQV FVVSRIREAV LAGTPTRQAV LDGVRRSASV
VTSAAVVMTT VFVSFVFLHL IEMKQIGFVL ATAVLIDAFV VRVLVLPSAM LLLGEATWWP
SRTRRAPKPV PARRPADVR
//
