ID A0A101R246_9ACTN Unreviewed; 420 AA.
AC A0A101R246;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Alpha-1-antitrypsin {ECO:0000313|EMBL:KUN40306.1};
GN ORFNames=AQJ30_06430 {ECO:0000313|EMBL:KUN40306.1};
OS Streptomyces longwoodensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68231 {ECO:0000313|EMBL:KUN40306.1, ECO:0000313|Proteomes:UP000053271};
RN [1] {ECO:0000313|EMBL:KUN40306.1, ECO:0000313|Proteomes:UP000053271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41677 {ECO:0000313|EMBL:KUN40306.1,
RC ECO:0000313|Proteomes:UP000053271};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces longwoodensis DSM 41677, type strain
RT for the species Streptomyces longwoodensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN40306.1}.
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DR EMBL; LMWS01000008; KUN40306.1; -; Genomic_DNA.
DR RefSeq; WP_067229741.1; NZ_KQ948550.1.
DR AlphaFoldDB; A0A101R246; -.
DR STRING; 68231.AQJ30_06430; -.
DR Proteomes; UP000053271; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053271};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..420
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039540675"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..228
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 420 AA; 44118 MW; 4EDECEE73905582A CRC64;
MIRTQRLAAG VCALLAALAS GIAFPAGAVA DETTALAPKV DLVLDVSGSM RTKDMDGGTR
MAAAKQAFNE VLDATPEEVQ LGIRTLGATY PGDDRKTGCK DTAQLYPVGP LDRTEAKSAV
ATLSPTGWTP IGPALLKAAD DLEGGEGSKR IVLISDGEDT CAPLDPCEVA REIAAKGIGL
TIDTLGLVPN TKMRAQLSCI AEATGGTYTS VEHTDDLTDK VNQLVDRAAD PVVTPVATEG
GSSCPKAPTL KSGLYTDREE FGQQRWYRVD VDPGKELRAS VSVAADRTMN PDYGLLVRAF
TTHGREIVRG EAAGGGRTDV ISTGLRYPKA DSDEEDAPAE TVCLLVTNSF SAASGVKTTP
GMPVELTVDV VDGPSQADDV ASFGLGRGWW LLGALVLIGF LAGLVWGWLS RWRVAVWRTN
//
