ID A0A101X987_9CREN Unreviewed; 199 AA.
AC A0A101X987;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=orotidine-5'-phosphate decarboxylase {ECO:0000256|ARBA:ARBA00012321};
DE EC=4.1.1.23 {ECO:0000256|ARBA:ARBA00012321};
GN ORFNames=AT715_07470 {ECO:0000313|EMBL:KUO87052.1};
OS Thermoproteus sp. JCHS_4.
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Thermoproteus.
OX NCBI_TaxID=1714258 {ECO:0000313|EMBL:KUO87052.1, ECO:0000313|Proteomes:UP000054781};
RN [1] {ECO:0000313|EMBL:KUO87052.1, ECO:0000313|Proteomes:UP000054781}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jay Z.J., Beam J.P., Kozubal M.A., Jennings R.D.E., Rusch D.B.,
RA Inskeep W.P.;
RT "The distribution, diversity and function of predominant Thermoproteales in
RT high-temperature environments of Yellowstone National Park.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway;
CC UMP from orotate: step 2/2. {ECO:0000256|ARBA:ARBA00004861}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO87052.1}.
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DR EMBL; LOBZ01000029; KUO87052.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A101X987; -.
DR STRING; 1714258.AT715_07470; -.
DR UniPathway; UPA00070; UER00120.
DR Proteomes; UP000054781; Unassembled WGS sequence.
DR GO; GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
DR GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR014732; OMPdecase.
DR InterPro; IPR001754; OMPdeCOase_dom.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR PANTHER; PTHR32119; OROTIDINE 5'-PHOSPHATE DECARBOXYLASE; 1.
DR PANTHER; PTHR32119:SF2; OROTIDINE 5'-PHOSPHATE DECARBOXYLASE; 1.
DR Pfam; PF00215; OMPdecase; 1.
DR SMART; SM00934; OMPdecase; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT DOMAIN 3..191
FT /note="Orotidine 5'-phosphate decarboxylase"
FT /evidence="ECO:0000259|SMART:SM00934"
SQ SEQUENCE 199 AA; 21097 MW; A50E23EBE1D3D65E CRC64;
MYPVVVALDV DLSKALAVAE SLRDEVAGFK VGWDLVLEAG LDSIKAVSRL GPVVVDLKLA
DIPYIVRRVV DKIAAAGACC AIAHGFLLPS LEKDERLYVL VKMTTGSRYD GLWRELLGQV
AGFRGAVAPG NEPQVVSAAR RALGCSARII SPGIGAQGGR PGDAIRAGAD FEIVGRYVLE
DPSRVSEWRG LKPACNDSI
//
