ID A0A117MKY5_9ACTN Unreviewed; 258 AA.
AC A0A117MKY5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase {ECO:0000313|EMBL:KUL22929.1};
GN ORFNames=ADL12_40880 {ECO:0000313|EMBL:KUL22929.1};
OS Streptomyces regalis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL22929.1, ECO:0000313|Proteomes:UP000053923};
RN [1] {ECO:0000313|Proteomes:UP000053923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DDAH family.
CC {ECO:0000256|ARBA:ARBA00008532}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL22929.1}.
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DR EMBL; LLZG01000391; KUL22929.1; -; Genomic_DNA.
DR RefSeq; WP_062712983.1; NZ_LLZG01000391.1.
DR AlphaFoldDB; A0A117MKY5; -.
DR OrthoDB; 3196313at2; -.
DR Proteomes; UP000053923; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR033199; DDAH-like.
DR PANTHER; PTHR12737:SF9; DIMETHYLARGININASE; 1.
DR PANTHER; PTHR12737; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE; 1.
DR SUPFAM; SSF55909; Pentein; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KUL22929.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053923}.
FT ACT_SITE 163
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
FT ACT_SITE 248
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
SQ SEQUENCE 258 AA; 27805 MW; 0D78C2B0461B2B3D CRC64;
MPSKKALIRR PSPRLAEGLV THIEREKVDV DLAVEQWEAY AEALRTHGWE TIEVDPADDC
PDSVFVEDTV VMYKNVALIT RPGAEARRDE TIGVEEAVAS LGCSVNWIWE PGTLDGGDVL
KVGDTIYVGR GGRTNAAGVQ QLRAAFEPLG ARVVTVPVSK VLHLKSAITA LPDGTILGRI
PQLDVPSLFP RFLPVPEESG AHVVLLGGGK LLMAASAPKT AELLADLGHE PVPVDISEFE
KLEGCVTCLS VRMRELYA
//
