ID A0A117QQI7_9ACTN Unreviewed; 800 AA.
AC A0A117QQI7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Peptidase M4 {ECO:0000313|EMBL:KUN41248.1};
GN ORFNames=AQJ30_02805 {ECO:0000313|EMBL:KUN41248.1};
OS Streptomyces longwoodensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68231 {ECO:0000313|EMBL:KUN41248.1, ECO:0000313|Proteomes:UP000053271};
RN [1] {ECO:0000313|EMBL:KUN41248.1, ECO:0000313|Proteomes:UP000053271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41677 {ECO:0000313|EMBL:KUN41248.1,
RC ECO:0000313|Proteomes:UP000053271};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces longwoodensis DSM 41677, type strain
RT for the species Streptomyces longwoodensis.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M4 family.
CC {ECO:0000256|ARBA:ARBA00009388}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN41248.1}.
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DR EMBL; LMWS01000004; KUN41248.1; -; Genomic_DNA.
DR RefSeq; WP_067228191.1; NZ_KQ948549.1.
DR AlphaFoldDB; A0A117QQI7; -.
DR STRING; 68231.AQJ30_02805; -.
DR Proteomes; UP000053271; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09597; M4_TLP; 1.
DR Gene3D; 3.10.170.10; -; 1.
DR Gene3D; 3.10.450.490; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR011096; FTP_domain.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR023612; Peptidase_M4.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR InterPro; IPR001570; Peptidase_M4_C_domain.
DR InterPro; IPR013856; Peptidase_M4_domain.
DR PANTHER; PTHR33794; BACILLOLYSIN; 1.
DR PANTHER; PTHR33794:SF1; BACILLOLYSIN; 1.
DR Pfam; PF07504; FTP; 1.
DR Pfam; PF05345; He_PIG; 1.
DR Pfam; PF01447; Peptidase_M4; 1.
DR Pfam; PF02868; Peptidase_M4_C; 1.
DR PRINTS; PR00730; THERMOLYSIN.
DR SUPFAM; SSF49313; Cadherin-like; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000053271};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..800
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007154614"
FT DOMAIN 82..118
FT /note="FTP"
FT /evidence="ECO:0000259|Pfam:PF07504"
FT DOMAIN 225..372
FT /note="Peptidase M4"
FT /evidence="ECO:0000259|Pfam:PF01447"
FT DOMAIN 375..549
FT /note="Peptidase M4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02868"
FT REGION 29..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 365
FT /evidence="ECO:0000256|PIRSR:PIRSR623612-1"
FT ACT_SITE 452
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR623612-1"
SQ SEQUENCE 800 AA; 81501 MW; 24E4D9E43D6F4859 CRC64;
MRRIPRKRTA VGAALLSTAA LLAVGLPSAP ASAQPAAPHP SPLRTGGLPA DLTPAQHATL
VRSAQADTAS TARSLGLGAQ EKLVVKDVVK DNDGTVHTRY ERTYAGLPVL GGDLVVHTPP
ASQAAGTVTT TFNNNRRTVK VASTTATYTK SAAEAKALTT ARSLDAQRPA ADSARKVIWA
GSGTPRLAWE TVVTGLQDDG TPSRLHVVTD ATSGAELYRF QDVKTGTGNT QYSGSVSLST
TLSGSTYQLY DTTRGGHKTY SLNAGTSGTG TLMTDADDVW GNGSGSNTQT AGADAAYGAQ
ETWDFYKNTF GRSGIRNDGV AAYSRVHYSS GYVNAFWDDS CFCMTYGDGS GNTHALTSLD
VAGHEMSHGV TSNTAGLDYS GESGGLNEAT SDIFGTGVEF YAGNSSDVGD YLIGEKININ
GDGTPLRYMD KPSKDGGSAD SWYSGVGNLD VHYSSGPANH MFYLLSEGSG SKTINGVTYN
SPTSDGVAVT GIGRAAALQI WYKALTTYMT SSTNYAGART AALNAAAALY GSGSTQYAGV
GNAFAGINVG GHITPPSSGV TVTNPGSQSS TVGTAVSLKI TASSTNSGAL TYAASGLPAG
LSINSSTGVI SGTPTTAGTY STTVTVTDST GASGTASFTW TVGTGGGGGT CTSAQLLGNP
GFESGNTTWT ASSGVITNDT GEAAHGGSYK AWLDGYGSTH TDTLSQSVAI PAGCKATLTF
YLHVDTAETT TSTAYDKLTV TAGSTTLATY SNLNKATGYT LRTLDLSSFA GSTVTLKFTG
AEDSSLQTSF VVDDTAVTTG
//
