ID A0A117RDG6_9ACTN Unreviewed; 801 AA.
AC A0A117RDG6;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=AQJ64_14590 {ECO:0000313|EMBL:KUN84719.1};
OS Streptomyces griseoruber.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1943 {ECO:0000313|EMBL:KUN84719.1, ECO:0000313|Proteomes:UP000052982};
RN [1] {ECO:0000313|EMBL:KUN84719.1, ECO:0000313|Proteomes:UP000052982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40281 {ECO:0000313|EMBL:KUN84719.1,
RC ECO:0000313|Proteomes:UP000052982};
RA Ruckert C., Winkler A., Kalinowski J., Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces griseoruber DSM 40281, type strain
RT for the species Streptomyces griseoruber.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUN84719.1}.
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DR EMBL; LMWW01000016; KUN84719.1; -; Genomic_DNA.
DR RefSeq; WP_055636696.1; NZ_LIQS01000407.1.
DR AlphaFoldDB; A0A117RDG6; -.
DR STRING; 1943.AQJ64_14590; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000052982; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.1120; Carboxypeptidase-like, regulatory domain; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR008969; CarboxyPept-like_regulatory.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF13620; CarboxypepD_reg; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 228..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..559
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 571..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 646..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..365
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 457..682
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 336..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 801 AA; 83834 MW; 69530209F9673E37 CRC64;
MARWCYRHRL VVLLLWVGAL FGLGFSASTA GTDYANVFSL PDTDSKKAYD LMEKAFPARA
GDTDTVVWKV DEGTVRDQDV RSRIQPALEK IAGMKGVGGV TSPYAGEQGG GQISRDGRIA
YAQITFADQA NAVPKELVQD VVDTARGAER GGLEVELGGQ AIQRVQEPPT GLAEMVGLVA
AAIVLFLAFG SLFAMLLPLA VAVFGVGTGL FSTQLLSHVT DIPDLAPLLS SLIGLGVGID
YALFIVTRHR KGILRGVAPE ESAVTALNTS GRAVLFAGGT VCIALAGMLV TNLRFLDGVV
VGTSLTVVLS VLAATTLLPA LLGFLGPRVL SRKQRRRLAA EGPEEERTSG PAARWSAEVQ
RRPRTIAVLA LVVMAVLALP VLSLRLGATD QGNNDASTTT RKAYDLLAEG FGPGFNGPLQ
VVVDGTDTTA LVRGIEDAPG VAQAAALPPA KGVTVIQVVP TTSPQSQETD TLIDRLRDDV
IPKAGVKAHV GGVTAVSKDF AAVTGDRLPL FVATIVGLGF LLLLIAFRSL VVPLTAAVMN
LIAAAASFGV LVAVFQWGWG LELLGLGKEG PINAFLPVIM LSLLFGLSMD YQVFLVSRMH
EEWVHTRDNA RAVRVGLAET SRVINSAALI MVCVFLAFVL SGDSGAAMAG VGLAAAVALD
AFILRTALVP AAMHLLGASN WWLPVWLEKR LPHLAVEPKE EDVTPSAGPS DGPATAVHGF
VRDVAGDPVE NASVALLSKG GRPLDQVTSL ADGSYILSAP APGTYLLSTT AASYTTQARQ
VTVGAEPLVH DVELAEMSEV N
//
