ID A0A117S1K5_9ACTN Unreviewed; 721 AA.
AC A0A117S1K5;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA methylase adenine-specific domain-containing protein {ECO:0000259|Pfam:PF02384};
GN ORFNames=AQJ91_13225 {ECO:0000313|EMBL:KUO20854.1};
OS Streptomyces dysideae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=909626 {ECO:0000313|EMBL:KUO20854.1, ECO:0000313|Proteomes:UP000053260};
RN [1] {ECO:0000313|EMBL:KUO20854.1, ECO:0000313|Proteomes:UP000053260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RV15 {ECO:0000313|EMBL:KUO20854.1,
RC ECO:0000313|Proteomes:UP000053260};
RA Ruckert C., Abdelmohsen U.R., Winkler A., Hentschel U., Kalinowski J.,
RA Kampfer P., Glaeser S.;
RT "Draft genome sequence of Streptomyces sp. RV15, isolated from a marine
RT sponge.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUO20854.1}.
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DR EMBL; LMXB01000031; KUO20854.1; -; Genomic_DNA.
DR RefSeq; WP_067020112.1; NZ_KQ949080.1.
DR AlphaFoldDB; A0A117S1K5; -.
DR STRING; 909626.AQJ91_13225; -.
DR OrthoDB; 9784823at2; -.
DR Proteomes; UP000053260; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.90.220.20; DNA methylase specificity domains; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR044946; Restrct_endonuc_typeI_TRD_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR42998:SF1; TYPE I RESTRICTION ENZYME HINDI METHYLASE SUBUNIT; 1.
DR PANTHER; PTHR42998; TYPE I RESTRICTION ENZYME HINDVIIP M PROTEIN-RELATED; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF116734; DNA methylase specificity domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000053260};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT DOMAIN 172..402
FT /note="DNA methylase adenine-specific"
FT /evidence="ECO:0000259|Pfam:PF02384"
FT REGION 528..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 721 AA; 76551 MW; 4EAFFFF7F52E139A CRC64;
MPDKPEPAPF VTAAEISRLA GVTRATVSNW RRRHADFPDP AGGSDASPLY DLQAVEGWLA
ARGQLPVGSP LDDVKAQLRR HPDGFEIAQR MSAVVLALVR IGEKGQKELL GCAAEALPAS
MGTVMRDHAA EVPGGAALTG FERGDEPVLR AVVRGVHETG AVPVLDALAE LPRDEAGVRG
AYATPAALVE LMADLVAGAG DSYPQSILDP ACGTGGLLVA AAERGATALY GQDVMPAQAG
QALARLGVLV PSAAAHMSDG DSLRHDAFPE LEAEAALCNP PYGDRDWGHD ELAYDARWEY
GLPPKGEPEL AWLQHCLSHL ASGGYAVLVL PPGTAERASG RRVRAELVRR GAVRAIVALP
TGIAPPLHVG LHLWVVQKPV HERPESLSIL FLDASAPGAL SDVRATGGRG EKMIDEEGLR
EAIARRWRAF VTSSETFETE PGIARAVGVV DLLDDVTDLT PARHTRATTV AVNPARFAEQ
MRKARTELAR AASTLTALND EGAWPMVGEK TRAWRTATVA DLARGAALSV QRAPSSTRNP
QAHGTTDRRE PGDGRRALTA ADVTAGQAAS GRVAEGQEAK AIEIMQGDIL LPEMLRPLDT
RARVADAQDA GNLLGPSLWL FRPDPERLDP WFLAGFLSAD ENVHSVATGS TMRRIDARRL
RVPLIPLNEQ REYGQAFRHL HALRAAAALA ARLASETTRE LKVGLTGGAL VPSTFGHTST
P
//
