ID A0A125Q1D7_9ACTN Unreviewed; 390 AA.
AC A0A125Q1D7;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Acetyl-CoA acyltransferase {ECO:0000313|EMBL:SCG75232.1};
GN ORFNames=GA0070623_3979 {ECO:0000313|EMBL:SCG75232.1};
OS Micromonospora rifamycinica.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=291594 {ECO:0000313|EMBL:SCG75232.1, ECO:0000313|Proteomes:UP000198226};
RN [1] {ECO:0000313|EMBL:SCG75232.1, ECO:0000313|Proteomes:UP000198226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44983 {ECO:0000313|EMBL:SCG75232.1,
RC ECO:0000313|Proteomes:UP000198226};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT607752; SCG75232.1; -; Genomic_DNA.
DR RefSeq; WP_067309185.1; NZ_LT607752.1.
DR AlphaFoldDB; A0A125Q1D7; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000198226; Chromosome i.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:SCG75232.1};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:SCG75232.1}.
FT DOMAIN 5..258
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 268..388
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
SQ SEQUENCE 390 AA; 40587 MW; 41CBAD4C390DF036 CRC64;
MSDAVIVGAV RTPVGRRKGG LAGIHPVDLS AHVLRALADR TGIDPGQVDD VIWGCVSQVG
EQSWNVARNG VLAAGWPETV PGTTLDRQCG SSQQALHFAA ATVLSGQADL VVAGGVESMT
RVPMGASVSD GTPFSAQLRE RYRGVEGFAD DQPLPFNQGV GAELIAARWR LSRAQLDEFA
LASHEKAAAA QDAGAFDPEL APVPLPDGGT VTADEGIRRD TSLAKLGELK TPFRKDGVVT
AGSASQISDG AAALAVTTAE WAGRHGLRPL ARVHTAVVAA DDPVTMLTAP IPATAKALRR
AGLGIEEIGV YEVNEAFAPV PLAWLAETEA DPERLNPRGG AIALGHPLGA SGVRIMTTML
QHMRDNDIRY GLQTMCEGGG MANATILELV
//
