ID A0A125YGL2_TOXGV Unreviewed; 813 AA.
AC A0A125YGL2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=B-related factor 1 {ECO:0000256|ARBA:ARBA00031009};
GN ORFNames=TGVEG_207900 {ECO:0000313|EMBL:ESS29369.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS29369.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TFIIB family.
CC {ECO:0000256|ARBA:ARBA00010857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS29369.1}.
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DR EMBL; AAYL02000305; ESS29369.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A125YGL2; -.
DR STRING; 432359.A0A125YGL2; -.
DR PaxDb; 5811-TGME49_007900; -.
DR EnsemblProtists; ESS29369; ESS29369; TGVEG_207900.
DR VEuPathDB; ToxoDB:TGVEG_207900; -.
DR eggNOG; KOG1598; Eukaryota.
DR OMA; ACLYAIC; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd20553; CYCLIN_TFIIIB90_rpt1; 1.
DR CDD; cd20554; CYCLIN_TFIIIB90_rpt2; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR011665; BRF1_TBP-bd_dom.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR013150; TFIIB_cyclin.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618:SF4; TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF07741; BRF1; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT DOMAIN 124..155
FT /note="TFIIB-type"
FT /evidence="ECO:0000259|PROSITE:PS51134"
FT REGION 108..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 813 AA; 88049 MW; 50B2AF12AD115E25 CRC64;
MREVRRPQRF VSASTSRSPL TFPSSSPRRV TLCFSSTSVF LQLRFEPSSS RSCWSPSALV
SAVFRPAFSH SFQGAGRPFR AAFSALLRVD FYCPPEVQKM LFGHADSGFP TGGRGEGEEE
GGKRSQSCRS CGSTELEANE SRGEIICCRC GTVLEDLTLV DGLQFAESSS GGVSMVGQFV
SSCTGAGRGL RAGVGGGGDS REQTLQRGFN NIQSIAERLR LSSQQHISSA HRLYLMATQR
NFTLGRRSVL VASACLYAIC RRERTPHLLI DFCDVLRTNV RALGQVFMKL LRVLHLQVPH
VDPSLFLERF ACQMQLGDKT HTVAQTGVRL IQAMNRDWIS TGRRPMGLCG AALLIAARYH
NFQMNAEDIA HIVRVSGPTV NRRLQEFKQT ATAQLAVADF ESTDLLSLPS QAQPPCRIKA
YRRKLKLMQK KEEETLALTD SPAVPALPST VPEEKKARMR SEEESDEPAE ANGAEQGENG
ESNRRETEEG EDVSLATVCG DSGPKRFAEF AAVGNLHLDT ELLCKEAPSP EDILMLAGRM
ASALDGRVQS NLSQSTSASC REDFGTQTDV SLDASVAGES RDTHRTAGES GGAEEGRTLS
LDASGTGQAG SEDLPPPSGT HGCRLRCSDV PASASSSASS SVSSSSASSS ILSGVVSRAS
CEDSEESRSV RSGGGRFGDT ETVGSTERGE EDDDSAEEEI RAMFLSESEQ RAKALIWDEL
TKDVMPLVHR RLKEKKLRER EMMLNQSKRK RLQSTGRRSR FGSDAGSAPA ASAAESVRLA
LQMSSRSIVG KINDDALNSL FGPVRRVTEQ NGN
//
