ID A0A126RVK2_9SPHN Unreviewed; 280 AA.
AC A0A126RVK2;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:AMK25635.1};
GN ORFNames=K426_23659 {ECO:0000313|EMBL:AMK25635.1};
OS Sphingobium sp. TKS.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1315974 {ECO:0000313|EMBL:AMK25635.1, ECO:0000313|Proteomes:UP000060779};
RN [1] {ECO:0000313|Proteomes:UP000060779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TKS {ECO:0000313|Proteomes:UP000060779};
RA Tabata M.;
RT "Whole genome sequence of gamma-HCH degrading bacterium Sphingobium sp.
RT TKS.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AMK25635.1, ECO:0000313|Proteomes:UP000060779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TKS {ECO:0000313|EMBL:AMK25635.1,
RC ECO:0000313|Proteomes:UP000060779};
RX PubMed=27056231;
RA Tabata M., Ohhata S., Kawasumi T., Nikawadori Y., Kishida K., Sato T.,
RA Ohtsubo Y., Tsuda M., Nagata Y.;
RT "Complete Genome Sequence of a gamma-Hexachlorocyclohexane Degrader,
RT Sphingobium sp. Strain TKS, Isolated from a gamma-Hexachlorocyclohexane-
RT Degrading Microbial Community.";
RL Genome Announc. 4:0-0(2016).
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DR EMBL; CP005084; AMK25635.1; -; Genomic_DNA.
DR RefSeq; WP_066562934.1; NZ_CP005084.1.
DR AlphaFoldDB; A0A126RVK2; -.
DR STRING; 1315974.K426_23659; -.
DR KEGG; spht:K426_23659; -.
DR PATRIC; fig|1315974.3.peg.4979; -.
DR OrthoDB; 9812907at2; -.
DR Proteomes; UP000060779; Chromosome 2.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22981; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR22981:SF80; BLR4309 PROTEIN; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000060779}.
FT DOMAIN 7..162
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT ACT_SITE 171
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 280 AA; 29496 MW; 600D3466D6845975 CRC64;
MTDTIRKIGF IGLGSMGGDQ ARELAKLPLD LTVYDVFPEA LAKFEGRAKL AASMAEVGED
ADAVGICVRD DTQVLECVDA LLPAMKRGAI LLIHSTIKPK TAQHIAERAA PLGIDVIDAP
VTRTEMSKDG PFVFCMTGGE ESVAARVQVV LNAFSTNTMH IGPLGSAMAL KICNNLVSWC
GIMLGIEVAN VAEASGVPMD KLLTVMKRNG NLTPPMAGFV DFRNNPGDAA RRAFFASQAG
IGEKDLALAE ELAAGADAVS PITSHTKTLL KKTLLAICES
//
