ID A0A126Z2M9_9MICO Unreviewed; 671 AA.
AC A0A126Z2M9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=AX769_11895 {ECO:0000313|EMBL:AMM20715.1};
OS Frondihabitans sp. PAMC 28766.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Frondihabitans.
OX NCBI_TaxID=1795630 {ECO:0000313|EMBL:AMM20715.1, ECO:0000313|Proteomes:UP000070552};
RN [1] {ECO:0000313|EMBL:AMM20715.1, ECO:0000313|Proteomes:UP000070552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC28744 {ECO:0000313|Proteomes:UP000070552};
RA Park H.;
RT "Complete genome of Frondihabitans sp.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CP014513; AMM20715.1; -; Genomic_DNA.
DR RefSeq; WP_066279535.1; NZ_CP014513.1.
DR AlphaFoldDB; A0A126Z2M9; -.
DR STRING; 1795630.AX769_11895; -.
DR KEGG; frp:AX769_11895; -.
DR OrthoDB; 9762169at2; -.
DR Proteomes; UP000070552; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd06577; PASTA_pknB; 3.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.10.20; -; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR NCBIfam; NF033483; PknB_PASTA_kin; 1.
DR PANTHER; PTHR45832:SF24; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00740; PASTA; 3.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51178; PASTA; 3.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000070552};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..275
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 381..448
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 520..587
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 588..665
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 671 AA; 70232 MW; 5B0B532853952430 CRC64;
MSASQSDPMI GRLIDGRYQV RSRIARGGMA TVYLASDLRL ERPVAVKIMH GHLADDENFK
ERFIQEARSA ARLAHPNVVN VFDQGQDDES AYLVMEYLPG ITLRELLQDH KMLTPEQATD
ILEAVLAGLA AAHKSGIVHR DLKPENVLLA DDGRIKIGDF GLARAASANT ATGAALLGTI
AYLSPELVTR GIADTRSDIY ALGIMLYEML TGEQPYKGEQ PMQIAYQHAN DTVPMPSAVN
PRVPPELDEL VLWATARDPD QRPRDARAML EHLFELQRGG SGGSPLNKTM VLPPAMAPVP
PLQRSTGPTG PVASGGTGDT MVLQKARHRT GPVAPALSTN AEALSRKAGS RRRRGLVWLI
VLIVLALLAA GTGWWFNAGP GANATVPRIA STSIPDATAR LKSAGFTVAA AQTGVYSVQI
PSGQVAGTRP AGGATVHKGS SVTLIVSKGP QILPLPTTLG QQETAAKALL KNFTVEASQY
QFGTQASGVV IGVTGKDSSG KAVDIGQAKT YPDKQPVTLT VSLGPVPNVV GQSLSNAQAT
LSNVNLTGAD TSDVFSDTVA SGVVISQAQA KAGSVHKGDT INLTVSKGPA PITVPDETGK
KVSAAEAALT ALGLKVTYAN CTTAECITAN ALGFDWRKLV KVSSQSPAGS AIAHKGDTIT
LQYDGSKVSI G
//
