ID A0A127W0B8_SPOPS Unreviewed; 339 AA.
AC A0A127W0B8;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=2-oxoisovalerate dehydrogenase {ECO:0000313|EMBL:AMQ06961.1};
GN ORFNames=AZE41_14015 {ECO:0000313|EMBL:AMQ06961.1};
OS Sporosarcina psychrophila (Bacillus psychrophilus).
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Sporosarcina.
OX NCBI_TaxID=1476 {ECO:0000313|EMBL:AMQ06961.1, ECO:0000313|Proteomes:UP000071057};
RN [1] {ECO:0000313|EMBL:AMQ06961.1, ECO:0000313|Proteomes:UP000071057}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6497 {ECO:0000313|EMBL:AMQ06961.1,
RC ECO:0000313|Proteomes:UP000071057};
RA Yan W.;
RT "Complete genome sequence of the Sporosarcina psychrophila DSM6497, a
RT psychrophila Bacillus that can mediate the Ca2+ precipitation.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP014616; AMQ06961.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A127W0B8; -.
DR STRING; 1476.AZE41_14015; -.
DR KEGG; spsy:AZE41_14015; -.
DR OrthoDB; 9771835at2; -.
DR Proteomes; UP000071057; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
FT DOMAIN 18..193
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 339 AA; 37458 MW; 8C163D2AD6653EB2 CRC64;
MMTQLKESDS KNETTKQMTL IQAINDGMRL MLDDDDRTII LGEDIGKNGG VFRATEGLQE
QFGDDRVVDT PLSEAGIIGT SIGLAVNGFR PVAEIQFLGF IYPAYEQIMT HVSRIRMRSM
SRFTVPIVIR APYGAGIRAP EIHSDSTEIL FTHMPGIKVV CPSNPYDAKG LLIAAMEDPD
PVLVLEPMKN YRSKREEVPV GKYTVEIGKG KIVRKGSDVT LIAWGAMISI AEKAAELAGK
KGISCEIIDL RTLYPIDRDI ITQSVQKTTR AVIIHEAHNT GGLGNDIVSI INDTAFLYLR
APIERVTGFD VPVPFFTLEE HYLPTTARVV EGIEKVLHF
//
