ID A0A132AE10_SARSC Unreviewed; 634 AA.
AC A0A132AE10;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 28-JUN-2023, entry version 30.
DE RecName: Full=Nuclear cap-binding protein subunit 1 {ECO:0000256|ARBA:ARBA00019879};
DE AltName: Full=80 kDa nuclear cap-binding protein {ECO:0000256|ARBA:ARBA00030965};
GN ORFNames=QR98_0077590 {ECO:0000313|EMBL:KPM09226.1};
OS Sarcoptes scabiei (Itch mite) (Acarus scabiei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Sarcoptoidea;
OC Sarcoptidae; Sarcoptinae; Sarcoptes.
OX NCBI_TaxID=52283 {ECO:0000313|EMBL:KPM09226.1, ECO:0000313|Proteomes:UP000616769};
RN [1] {ECO:0000313|EMBL:KPM09226.1, ECO:0000313|Proteomes:UP000616769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:KPM09226.1};
RX PubMed=26555130; DOI=10.1186/s13071-015-1198-2;
RA Rider S.D.Jr., Morgan M.S., Arlian L.G.;
RT "Draft genome of the scabies mite.";
RL Parasit. Vectors 8:585-585(2015).
CC -!- SUBUNIT: Component of the nuclear cap-binding complex (CBC), a
CC heterodimer composed of Cbp80 and Cbp20 that interacts with m7GpppG-
CC capped RNA. {ECO:0000256|ARBA:ARBA00011361}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NCBP1 family.
CC {ECO:0000256|ARBA:ARBA00007413}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM09226.1}.
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DR EMBL; JXLN01013292; KPM09226.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A132AE10; -.
DR VEuPathDB; VectorBase:SSCA009239; -.
DR OMA; TMQLECI; -.
DR OrthoDB; 5477544at2759; -.
DR Proteomes; UP000616769; Unassembled WGS sequence.
DR GO; GO:0005846; C:nuclear cap binding complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000339; F:RNA cap binding; IEA:InterPro.
DR GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027159; CBP80.
DR InterPro; IPR015172; MIF4G-like_typ-1.
DR InterPro; IPR015174; MIF4G-like_typ-2.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR12412; CAP BINDING PROTEIN; 1.
DR PANTHER; PTHR12412:SF2; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF09088; MIF4G_like; 1.
DR Pfam; PF09090; MIF4G_like_2; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
PE 3: Inferred from homology;
KW mRNA capping {ECO:0000256|ARBA:ARBA00023042};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
SQ SEQUENCE 634 AA; 73952 MW; ADE7D7F2EF76801A CRC64;
MFKRRYTDVD REYHSILNVV NILSNSSVED EERYSKKARF NNVPEESIED KLDELIVKIG
EKVTVVEFPQ KICIYSTLIG LLNVRNYSFG GNVVEKLITS LRNHLKNGEY EKARIVVRFF
SDLVNTRVIS TASLINLFEN LVDVTMEDNI PQVRSDYFVY MVLSALPWVG KELYEKKEQE
LDQILNMIDS YMNKRDKNDY HSALKVWHSD NPHPQEEYLS CLWNQITRLQ SNKWVENHIY
RPYIHFDSTL CEALQHNLVS IKPPPHESTN FYPYPEIVFR LFDYTDCPEK SILPSNHSID
RYLIEDNLRS IFNSTCFDRK DCATALLNYT NLSIATKIPL EYIIVEVIFG EMFRLPLSKY
PAIAYGSIFL DLCKLMPSTF PQVLAQTVEL LFDRLDTMNG ACIDRFASWF AYHLSNFQFR
WGWDEWTISL KNDPLHPKCK FISETFHYCL RLSYHAKIIE SVPEAFHKLC PKLPKLVDKY
PNAEDKDDQL DFTMTNETTK TIKDNVESVR DILGQKCSVE DCLELLKDIT DESDESDSNK
LRIEIFVNVL LNVSSKSMTH AFAYIAKYRD VLKQLNTDEE AQLQMMNTML EVCSSHQQVA
NLNCTSVEES SIFFAIAFNN LDRKADEIRS FEIS
//
